Explanation When 1 mol of amino acid is linked to the chain of protein, this results in the formation of a peptide bond between free carboxyl end of protein chain and amino group of coming amino acid. The chemical reaction for the formation of an amide linkage, considering glycine amino acidis shown as: -NHCO ( CH 2 ) NHCO ( CH 2 ) NH 2 + COOH ( CH 2 ) NH 2 → -NHCO ( CH 2 ) NHCO ( CH 2 ) NH-CO ( CH 2 ) NH 2 + H 2 O Hydrolysis for formation of an amide linkage can be determined as follows: dH = BE ( reactant ) - BE ( product ) Here, BE (C-C) = 83 kcal mol-1 BE (C-H) = 99 kcal mol-1 BE (C-O) = 85.5 kcal mol-1 BE (O-H) = 111 kcal mol-1 BE (C=O) ( aldehyde )= 177 kcal mol-1 Putting the values, dH = [ 2 BE ( CC ) + 4 BE ( NH ) + 2 BE ( NC ) + 2 BE ( C=O ) + 4 BE ( CH ) ] + [ 1 BE ( CC ) + BE ( C=O ) + BE ( C-O ) + BE ( OH ) + 2 BE ( CH ) + 2 BE ( NH ) + 1 BE ( NC ) ] &

8th Edition

ISBN: 9781305079373

Author: William L. Masterton, Cecile N. Hurley

Publisher: Cengage Learning

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Question

Chapter 23, Problem 50QAP

Interpretation Introduction

Interpretation:

The hydrolysis energy for formation of an amide bond when 1 mole of amino acid is added to the chain needs to be determined.

Concept introduction:

Amino acids combine to form protein, this results in the formation of a peptide bond between the protein chain and the coming amino acid. Bond is formed between the carbon and nitrogen atom; this is known as amide linkage.

Bond energy is the energy required for the formation or breaking the bond present between the atom of a molecule.

Hydrolysis for formation of an amide linkage can be determined as follows:

dH = BE (reactant) - BE (product)

Expert Solution & Answer

Chapter 23 Solutions

Chemistry: Principles and Reactions

Ch. 23 - Prob. 1QAP Ch. 23 - Prob. 2QAP Ch. 23 - Prob. 3QAP Ch. 23 - Prob. 4QAP Ch. 23 - Prob. 5QAP Ch. 23 - Prob. 6QAP Ch. 23 - Prob. 7QAP Ch. 23 - Prob. 8QAP Ch. 23 - Prob. 9QAP Ch. 23 - Prob. 10QAP

Ch. 23 - Prob. 11QAP Ch. 23 - Prob. 12QAP Ch. 23 - Prob. 13QAP Ch. 23 - Prob. 14QAP Ch. 23 - Prob. 15QAP Ch. 23 - Prob. 16QAP Ch. 23 - Prob. 17QAP Ch. 23 - Prob. 18QAP Ch. 23 - Prob. 19QAP Ch. 23 - Prob. 20QAP Ch. 23 - How many chiral carbon atoms are there in ...Ch. 23 - How many chiral carbon atoms are there in sucrose?...Ch. 23 - Prob. 23QAP Ch. 23 - Give the structural formulas of two different...Ch. 23 - (a) How many tripeptides can be made from glycine,...Ch. 23 - Prob. 26QAP Ch. 23 - Prob. 27QAP Ch. 23 - Prob. 28QAP Ch. 23 - For alanine, Ka1=5.1105,Ka2=1.81010 . Calculate...Ch. 23 - Prob. 30QAP Ch. 23 - On complete hydrolysis, a polypeptide gives two...Ch. 23 - Prob. 32QAP Ch. 23 - Prob. 33QAP Ch. 23 - Prob. 34QAP Ch. 23 - Prob. 35QAP Ch. 23 - Prob. 36QAP Ch. 23 - Prob. 37QAP Ch. 23 - Prob. 38QAP Ch. 23 - Prob. 39QAP Ch. 23 - Prob. 40QAP Ch. 23 - Prob. 41QAP Ch. 23 - Sketch the form in which leucine would exist in...Ch. 23 - How many tripeptides could one make from glycine,...Ch. 23 - A 1.00-mg sample of a pure protein yielded on...Ch. 23 - Describe what is meant by (a) the primary...Ch. 23 - Glycolysis is the process by which glucose is...Ch. 23 - Plants synthesize carbohydrates from CO2 and H2O...Ch. 23 - Prob. 48QAP Ch. 23 - Prob. 49QAP Ch. 23 - Prob. 50QAP Ch. 23 - Prob. 51QAP Ch. 23 - Aspartic acid acts as a triprotic acid with...

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Biomolecules - Protein - Amino acids; Author: Tutorials Point (India) Ltd.;https://www.youtube.com/watch?v=ySNVPDHJ0ek;License: Standard YouTube License, CC-BY

Solution Summary: The author explains the hydrolysis energy for formation of an amide bond when 1 mole of amino acid is added to the chain of protein.

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Chapter 23 Solutions