Concept explainers
Interpretation:
The approach of
Concept introduction:
In bimolecular nucleophilic substitution reactions (
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- Consider the molecule shown below. There are at least 4 different locations that a nucleophile can react. Draw 4 different intermediates that could be formed for reaction of nucleophile at 4 different locations (use Nu for nucleophile). A H H,CO D Which intermediate do you think would be more stable? A B C or D Why would it be more stable?arrow_forwardIn Part 1. choose the most "electron-rich" atom in the reaction below, In Part 2. identify the elementary mechanistic step. Part 1 sitnl See Periodic Table See Na-ö: H,C-ö: Na-r: Part 2 Select the elementary mechanistic step: Choose one: O nucleophilic elimination O nucleophilic substitution O carbocation rearrangement O electrophilic additionarrow_forward2. Number all atoms (except Hs), add lone pairs, add formal charges, and give the mechanism arrows for the reaction below of HO + Br + Brarrow_forward
- Which SN2 reaction will occur most rapidly? (Assume the concentrations and temperatures are all the same.) * CH;0 + ^CI CH3 + CI- CH, B CH,0 + CH + F CH,O + CH, CH,O Br Br Darrow_forward10. Draw the product(s) of the given curved arrows. Label the arrows as Ip→л, п→lp, n → п, lp→a, a →lp, etc. Br OH HO) OH (+) H H НО н. Ф нarrow_forwardDetermine the mechanism and product for the given reaction by adding atoms, bonds, nonbonding electron pairs, and curved arrows. Acid and water are added in the second step. CH₂CH₂MgBr 2 Step 1: Add curved arrows. * MB Br → product Et₂ O Step 2: Aqueous workup. Complete the intermediate, then add curved arrows for the workup step. H : CLT: Mg Brarrow_forward
- On the lowest energy pathway to form the product of the following reaction, which species is a plausible transition state? (Dotted lines represent bonds in the process of forming or breaking.) x● HBr H---Br Br-H H----Br ठ Br-H productarrow_forward4. Rank the following reactions in terms of rate for an SN2 reaction (1 = fastest reaction). Are any of these reactions not possible? Br OH NaOH NaOH OMS NaOH NaOHarrow_forwardPredict the products of this organic reaction: CH3 CH₂ || No reaction CH3 | O−CH–CH2–CH3 + KOH A Specifically, in the drawing area below draw the structure of the product, or products, of this reaction. (If there's more than one product, draw them in any arrangement you like, so long as they aren't touching.) If there aren't any products because this reaction won't happen, check the No reaction box under the drawing area. Click anywhere to draw the first atom of your structure. X Ś Ćarrow_forward
- Predict the products of this organic reaction: CH3 CH₂ || No reaction CH3 -CH-CH₂-CH3 + NaOH A Specifically, in the drawing area below draw the structure of the product, or products, of this reaction. (If there's more than one product, draw them in any arrangement you like, so long as they aren't touching.) If there aren't any products because this reaction won't happen, check the No reaction box under the drawing area. ? Click anywhere to draw the first atom of your structure. X Śarrow_forward4. Use the reactant below to perform two separate reactions. Give the mechanism(s) and product(s) for each reaction. Show stereochemistry and be clear in your work. Use chair form. KOEt, EtOH t-Bu |||| H3O+arrow_forwardConsider this reaction: Br CH;OH Br-Br H3CO The mechanism proceeds through a first cationic intermediate, intermediate 1. Nucleophilic attack leads to intermediate 2, which goes on to form the final product. In cases that involve a negatively charged nucleophile, the attack of the nucleophile leads directly to the product. Br + CH3OH Br Intermediate 1 Intermediate 2 (product) In a similar fashion, draw intermediate 1 and intermediate 2 (final product) for the following reaction. OH + Br2 + HBr Br racemic mixturearrow_forward
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