(a)
To write:
The mechanism of transport of IgG antibodies with the help of receptor FcRn across cellular barriers, and the involvement of specific cell barrier.
Introduction:
IgG antibody binds to FcRn receptor on the apical side of the endothelial cell membranes in blood capillary walls and further transferred from the blood into the extracellular spaces through receptor-mediated transcytosis process. IgG reaches to the fetal blood by crossing the placental barrier and remain active for 6 months until the body begins to produce its own IgG.
(b)
To write:
Denote the ultimate location of transported material.
Introduction:
IgG antibody binds to FcRn receptor on the apical side of the endothelial cell membranes in blood capillary walls and further transferred from the blood into the extracellular spaces through receptor-mediated transcytosis process. IgG reaches to the fetal blood by crossing the placental barrier and remain active for 6 months until the body begins to produce its own IgG.
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