Brock Biology of Microorganisms (14th Edition)
14th Edition
ISBN: 9780321897398
Author: Michael T. Madigan, John M. Martinko, Kelly S. Bender, Daniel H. Buckley, David A. Stahl, Thomas Brock
Publisher: PEARSON
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Textbook Question
Chapter 8.7, Problem 1MQ
- Give one example each of T4 early, middle, and late proteins.
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T cells can differentiate into 5 different subsets of helper T cells. Answer the following questions for TH1 cells:
A) In general, list three unique factors that differentiate the TH1 subset from the other subsets.
B) For each of those factors identified in A, provide one specific example that applies to TH1 cells.
C) What type of pathogens are targeted by the TH1 cells?
Draw a schematic diagram of a typical IgG molecule and label each of the following parts: H chains, L chains, intrachain disulfide bonds, hinge, Fab, Fc, and all the domains. Indicate which domains are involved in antigen binding.
c) State some of the features that cross the cell membrane and make "porin proteins" specific.
d) Briefly clarify the concepts of "acylation", "prenylation" and "GPI stabilizer" in the context of membrane protein interactions.
e) When determining ABO Blood Groups, give information about which blood group data can be obtained depending on the interaction of which antigens in the red blood cell and which antibodies in the serum.
Chapter 8 Solutions
Brock Biology of Microorganisms (14th Edition)
Ch. 8.1 - How does a virus differ from a cell?Ch. 8.1 - Why does a virus need a host cell?Ch. 8.1 - Compared with cells, what is unusual about viral...Ch. 8.2 - Distinguish between a capsid and a capsomere. What...Ch. 8.2 - What is the difference between a naked virus and...Ch. 8.2 - What kinds of enzymes can be found within the...Ch. 8.3 - What is packaged into capsids during maturation?Ch. 8.3 - Explain the term burst size.Ch. 8.3 - Prob. 3MQCh. 8.4 - What is meant by a viral titer?
Ch. 8.4 - What is a plaque-forming unit?Ch. 8.4 - What is meant by the term plating efficiency?Ch. 8.5 - How does attachment contribute to virushost...Ch. 8.5 - Prob. 2MQCh. 8.5 - What part of phage T4 enters the host cytoplasm?
Ch. 8.6 - Prob. 1MQCh. 8.6 - Prob. 2MQCh. 8.6 - Prob. 3MQCh. 8.7 - Give one example each of T4 early, middle, and...Ch. 8.7 - Prob. 2MQCh. 8.7 - What is required to package the T4 genome into its...Ch. 8.8 - What is a lysogen and what is a prophage?Ch. 8.8 - How does DNA replication in lambda differ from...Ch. 8.8 - What commits lambda to the lytic versus the...Ch. 8.9 - Prob. 1MQCh. 8.9 - Prob. 2MQCh. 8.9 - Prob. 3MQCh. 8.10 - Prob. 1MQCh. 8.10 - Prob. 2MQCh. 8.10 - Prob. 3MQCh. 8.11 - What type of bacteriophages are most common in the...Ch. 8.11 - Prob. 2MQCh. 8.11 - Prob. 3MQCh. 8 - Prob. 1RQCh. 8 - Prob. 2RQCh. 8 - Prob. 3RQCh. 8 - Why does a one-step growth curve differ in shape...Ch. 8 - Describe the events that occur on an agar plate...Ch. 8 - Prob. 6RQCh. 8 - What is required for a bacteriophage T4 virion to...Ch. 8 - Prob. 8RQCh. 8 - Prob. 9RQCh. 8 - Bacteriophage T4 lacks its own RNA polymerase. How...Ch. 8 - Prob. 11RQCh. 8 - Prob. 12RQCh. 8 - Prob. 13RQCh. 8 - Prob. 14RQCh. 8 - Why can it be said that the retrovirus genome is...Ch. 8 - Prob. 16RQCh. 8 - Prob. 17RQCh. 8 - What causes the viral plaques that appear on a...Ch. 8 - The promoters on genes encoding early proteins in...Ch. 8 - Under some conditions, it is possible to obtain...Ch. 8 - Prob. 4AQ
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- Describe the structural features of a typical immune-globulin molecule.arrow_forwardDescribe the structure and basic functions of the five major typesof immunoglobulins.arrow_forwardWhat is an immunoglobulin? Describe the structure of an immunoglobulin molecule (light chain and heavy chain).arrow_forward
- Describe the structure of immunoglobulin and the functions of the Fab and Fc portions.arrow_forwardSamantha tells her doctor that she has been feeling jittery and has had trouble falling asleep. She complains that her roommates always set the thermostat too high. Blood tests reveal antibodies that suggest an autoimmune disease. Explain Samantha’s symptoms. What organ are theantibodies binding to and how does this cause her symptoms?arrow_forwardDifferentiate the types of immunoglobulins. Please make a table.arrow_forward
- Consider a pencil-shaped protein with two epitopes, Y (the “eraser” end) and Z (the “point” end). They are recognized by antibodies A1 and A2, respectively. Draw and label a picture showing the antibodies linking proteins into a complex that could trigger endocytosis by a macrophage.arrow_forwardDifferentiate protein complementation from supplementation? Give a concrete example in each category.arrow_forwardName the two types of antibody light chains.arrow_forward
- (35) Human immunization with purified polysaccharide antigens generates a response that is not dependent on T-lymphocytes control. As a result switching of immunoglobulin class during immune response does not occur . Therefore,the human immune response 2 months after vaccination with purified polysaccharide involves primarily which of the following immunoglobulin classes? (A) IgA. (B) IgD. (C) IgE. (D) IgG.…arrow_forwardDo T cells bear a cell-surface receptor capable of recognizing a specific antigen?arrow_forwardThe ends of each heavy chain and light chain in an immunoglobulin make up the antigen-binding sites. The end of one of these chains is shown here. Biochemists tend to classify protein structures into four groups: mostly alpha, mostly beta, mixed alpha and beta, or neither alpha nor beta. Based on the model shown here, how would you classify this part of the immunoglobulin protein? The loopy polypeptide segments at the very top of the structure shown are the segments that actually contact the antigen. Would you expect these binding segments to be rigid or flexible?arrow_forward
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