Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Do T cells bear a cell-surface receptor capable of recognizing a specific antigen?
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- Select the type of T cell that plays a role in diminshing an immune response: a) TH17 b) TREG c) TC d) TH1arrow_forwardIn what way does the T cell’s membrane receptors differ from the B cell’s membrane receptor? In other words, what will each bind to?arrow_forwardWhich type of T cell participates in both cell-mediated and antibody-mediated immune responses?arrow_forward
- Identify some PAMPs that are recognized by PRRs.Which cells express PRRs? How do PRRs associate withPAMPs to promote innate immunity?arrow_forwardWhat is the relationship and differences between receptor-mediated endocytosis and TLR in relation to innate immunity?arrow_forwardAre memory t cells responsible for directing immune response?arrow_forward
- All of the following statements concerning regulatory T cells (Treg) are correct, EXCEPT: The regulatory cytokines produced by regulatory T cells are IL-12 and TGF-B O Thymocytes that recognize self-antigen in the thymus with a certain affinity become natural (central) regulatory T cells O In the periphery T cells that recognize self-antigen in the presence of TGF-B become induced regulatory T cells O A Treg cell can suppress self-reactive lymphocytes that recognize peptides different from that recognized itself provided that the peptides are derived from the same tissue O A Treg cell can suppress self-reactive lymphocytes that recognize peptides different from that recognized by itself provided that the peptides are presented by the same antigen-presenting cell (APC)arrow_forwardThe innate immune response together with antibodies are generally not effective at clearing infections established by pathogens that replicate inside host cells. The evolution of T cells has provided a means for the immune response to ‘see’ intracellular infections based on the ability of T cells to: Secrete cytokines that diffuse into the infected tissue Activate type I interferon production by macrophages and dendritic cells Activate macrophages to induce inflammation Recognize pathogen-derived peptides on host MHC surface molecules Express cytoplasmic sensors for detecting pathogen-derived nucleic acidsarrow_forwardDescribe the differences in how an antigen presenting cells (APC) activate a Helper T versus a Cytotoxic T cell.arrow_forward
- Generally speaking, what kinds of cells express MHC I, MHC II, or both? What is presented on MHC I and II, and what kind of T cell recognizes each one? What response occurs when a T cell recognizes what is being presented on MHC I? What happens if it recognizes MHC II? Give an example of each type of recognition.arrow_forwardWhich type of MHC-class molecule is found on all nucleated cells and is used to communicate with cytotoxic T-lymphocytes? Which classes are displayed on APCs, and which class is used specifically to communicate with (a) helper T-lymphocytes and (b) cytotoxic T-lymphocytes?arrow_forwardDescribe how T cell-mediated immunity fights against pathogens.arrow_forward
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