To determine:
Whether the given pedigree is consistent with autosomal dominant inheritance.
Introduction:
Ectrodactyly is an autosomal dominant trait. It is a rare condition in which few fingers are absent and the hand or foot is split. Thus, it is also known as split hand or split foot. In 2011, it was found that novel mutation in DLX5 gene results in malformation of split hand or foot.
To determine:
The mode of inheritance, if the trait is not autosomal dominant.
Introduction:
Ectrodactyly is an autosomal dominant trait. The autosomal dominant genetic disorder occurs when the dominant allele for a particular trait is responsible for the expression of the disease, either present in homozygous or heterozygous condition.
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