Interpretation:
By analogy about nucleophilic substitution reactions in simple systems, the product for each of the given reactions is to be predicted.
Concept introduction:
Primary alkyl halide undergoes predominantly
reaction is a one-step concerted process. The
Generally, it is true that the less basic the leaving group, the smaller the energy requirement for cleaving its bond to carbon and the faster the rate. Thus, good leaving groups are weak bases.
Primary alkyl chlorides react with sodium acetate to yield the corresponding acetate esters.
Hydrolysis of
Alkyl sulfonates are derivatives of sulfonic acids prepared by treating an alcohol with the appropriate sulfonyl chloride, usually in the presence of pyridine. Alkyl sulfonates undergo nucleophilic substitution similar to alkyl halides.
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- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning