Concepts of Biology
1st Edition
ISBN: 9781938168116
Author: Samantha Fowler, Rebecca Roush, James Wise
Publisher: OpenStax College
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Chapter 6, Problem 15CTQ
Explain the difference between a proto-oncogene and a tumor suppressor gene.
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Define oncogene, proto-oncogene, and tumor-suppressor gene.
Define tumor-suppressor genes. Why is a mutation in a single copy of a tumor-suppressor gene expected to behave as a recessive gene?
Explain why mutations in tumor suppressor genes are recessive (both copies of the gene must be defective for the regulation of cell division to be defective), whereas mutations in oncogenes are dominant.
Chapter 6 Solutions
Concepts of Biology
Ch. 6 - Figure 6.4 Which of the following is the correct...Ch. 6 - A diploid cell has _ ____ the number of...Ch. 6 - An organism’s traits are determined by the...Ch. 6 - Chromosomes are duplicated during what portion of...Ch. 6 - Separation of the sister chromatids is a...Ch. 6 - The individual chromosomes become visible with a...Ch. 6 - What is necessary for a cell to pass the G2...Ch. 6 - ________ are changes to the nucleotides in a...Ch. 6 - A gene that codes for a positive cell cycle...Ch. 6 - Which eukaryotic cell-cycle event is missing in...
Ch. 6 - FtsZ proteins direct the formation of a ________...Ch. 6 - Compare and contrast a human somatic cell to a...Ch. 6 - Describe the similarities and differences between...Ch. 6 - Outline the steps that lead to a cell becoming...Ch. 6 - Explain the difference between a proto-oncogene...Ch. 6 - Name the common components of eukaryotic cell...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What is the difference between a proto-oncogene and a tumor-suppressor gene?arrow_forwardWhich of the following mutations will result in cancer? a. homozygous recessive mutation in a tumor-suppressor gene coding for a nonfunctional protein b. dominant mutation in a tumor-suppressor gene in which the normal protein product is overexpressed c. homozygous recessive mutation in which there is a deletion in the coding region of a proto-oncogene, leaving it nonfunctional d. dominant mutation in a proto-oncogene in which the normal protein product is overexpressedarrow_forwardExplain the difference between a proto-oncogene and a tumor-suppressor gene.arrow_forward
- Describe the difference between a tumor suppressor and an oncogene with respect to the actual causes of cancer.arrow_forwardDefine tumor-suppressor genes. Why is a mutated single copy of a tumor-suppressor gene expected to behave as a recessive gene?arrow_forwardExplain Mutations in tumor-suppressor genes are recessive at the cellular level but dominant at the organismal level.arrow_forward
- Compare and contrast oncogenes and tumor suppressors. Contrast oncogenes and proto-oncogenes. Describe the types of mutations that convert proto-oncogenes into oncogenes. Summarize some functions of common oncogenes in cell survival and uncontrolled growth. Contrast tumor suppressors to oncogenes. Describe the types of mutations in tumor suppressors that are found in common cancers. Summarize the functions of common tumor suppressors in cell survival and cell growth.arrow_forwardDescribe the genetic changes that inactivate tumor-suppressor genes.arrow_forwardDefine the following terms: tumor, neoplasia, anaplasia, metastasis, proto-oncogene, oncogene, and tumor suppressor gene.arrow_forward
- Explain about the TP53 Tumor-suppressor Gene ?arrow_forwardExplain the difference between proto-oncogene and tumor suppressor mutations in terms of its potential to cause cancer.arrow_forwardTissues and differentiation: a) Explain what is meant by determination and differentiation b) Explain the difference between an oncogene and a tumor suppressor gene and describe how they are involved in the development of cancerarrow_forward
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