Chapter 6, Problem 11RQ

The following events apply to the endochondral ossi�cation process as it

occurs in the primary ossi�cation center. Put these events in their proper order by

assigning each a number (1-6).

(a) $\text{\_\_\_}$ Cartilage in the diaphysis calci�es, and chondrocytes die and

disintegrate, leaving cavities.

(b) $\text{\_\_\_}$ A collar of bone is laid down around the hyaline cartilage model

just deep to the periosteum.

(c) $\text{\_\_\_}$ The periosteal bud invades the center of the diaphysis.

(d) $\text{\_\_\_}$ The perichondriurn of shaft becomes more vascularized and

becomes a periosteum.

(e) $\text{\_\_\_}$ Osteoblasts �rst deposit bone tissue around the cartilage spicules

within the diaphysis.

(f) $\text{\_\_\_}$ Osteoclasts remove the bone from the center of the diaphysis,

leaving a medullary cavity that then houses marrow.