Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 5, Problem 6P

In Drosophila, the map positions of genes are given in mapunits numbering from one end of a chromosome to theother. The X chromosome of Drosophila is 66 m .u . long.The X-linked gene for body color with two alleles, y+ forgray body and y for yellow body resides at one end ofthe chromosome at map position 0 .0 . A nearby locus foreye color, with alleles w+ for red eye and w for white eye, is located at map position 1 .5 . A third X-linked gene, controlling bristle form, with f+ for normal bristles and f forforked bristles, is located at map position 56 .7 . Each generesides on the X chromosome, and at each locus the wildtype allele is dominant over the mutant allele.

a. In a cross involving these three X-linked genes, do youexpect any gene pair(s) to show genetic linkage? Explainyour reasoning.

b. Do you expect any of these gene pair(s) to assort independently? Explain your reasoning.

c. A wild - type female fruit fly with the genotype y+w+f/ ywf+ is crossed to a male fruit fly that has yellow body, white eye, and forked bristles. Predict the frequency of each progeny phenotype class produced by this mating

d. Explain how each of the predicted progeny classes isproduced.

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In Drosophila flies, the allele b gives a black body, and the allele b+ gives brown, the wild-typephenotype. The allele wx of a separate gene gives waxy wings, and wx+ gives non-waxy. The allele cn ofa third gene gives cinnabar eyes, and cn+ gives red. A female heterozygous for these three genes istestcrossed, and 745 progenies are produced which are phenotypically classified as follows:5 b+ wx+ cn+4 b wx cn53 b+ wx cn 49 b wx+ cn+287 b+ wx+ cn279 b wx cn+ 33 b+ wx cn+35 b wx+ cn Make a linkage map of the three genes. Compute for interference and explain what the derived valuemeans. Show complete solutions to support your answers.
In Drosophila, the genes st (scarlet eyes), ss (spineless bris- tles), and e (ebony body) are located on chromosome 3, with map positions as indicated: st SS e 44 58 70 Each of these mutations is recessive to its wild-type allele (st*, dark red eyes; ss*, smooth bristles; e*, gray body). Phenotypically wild-type females with the genotype st ss e*/st* st* ss+ e were crossed with triply recessive males. Predict the phenotypes of the progeny and the frequen- cies with which they will occur assuming (a) no interfer- ence and (b) complete interference.
In Drosophila, three autosomal genes have the following map:20 m.u. 10 m.u.a b ca. Provide the data, in terms of the expected numberof flies in the following phenotypic classes, whena+ b+ c+/ a b c females are crossed to a b c / a b c males. Assume 1000 flies are counted and that nointerference exists in this region.a+ b+ c+a b ca+ b ca b+ c+a+ b+ ca b c+a+ b c+a b+ cb. If the cross was reversed, such that a+ b+ c+ / a b cmales are crossed to a b c / a b c females, howmany flies would you expect in the same phenotypic classes?

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Genetic Analysis: An Integrated Approach (3rd Edition)

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