Pathophysiology
6th Edition
ISBN: 9780323354813
Author: Jacquelyn L. Banasik PhD ARNP
Publisher: Saunders
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Chapter 5, Problem 2KQ
Summary Introduction
The hereditary material or a genetic potential of a living thing is referred to as genetic material. It is carried in the form of base sequences of DNA (deoxyribonucleic acid) as per the genetic code. The genetic code is made up of four bases, namely Adenine (A), Guanine (G), Thymine (T), and Cytosine (C). The DNA is transcribed into mRNA (messenger RNA) in which one of the base Thymine is replaced by Uracil (U). The mRNA is then translated into proteins.
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- Which of the following DNAs is most likely to contain the recognition sequence for a homodimeric DNA binding protein? (Note that only one strand of the DNA is shown - you will find it helpful to write down the sequence and the sequence of the opposite strand to answer this question.) a) 5’- G A G C G A T C G C T C - 3’ b) 5’- G A G C G A G A G C G A - 3’ c) 5’- G A G C G A A G C G A G - 3’arrow_forward1) a) Sketch an A-form helix and a B-form helix, highlighting the differences between them. Indicate the bases and backbone as lines. Label the major and minor grooves. 2) Sketch a ribose in the pucker that is expected in RNA. 3) Sketch a 2’ deoxyribose in the pucker that is expected in DNA. 4) Draw a GCG triplet (GC Watson-Crick), with perfect geometry. Draw the bases only, with dR’s at the N-9 positions of the purines (Gs) and at the N1 positions of the pyrimidine (C)arrow_forwardb) For a DNA strand with the given genetic code of bases , undergoing transcription, what will be the complimentary RNA strand? Provide the direction as well as 5" and 3" indicators for the new genetic genome. 5" G-A-A-C-T-G-G-A^T-T-C-T-A-C-C3'.arrow_forward
- What holds the two strands of a DNA double helix together? A) hydrogen bonds between bases B) hydrogen bonds between phosphates C) hydrophobic bonds between bases D) hydrophobic bonds between sugars E) phosphate bondsarrow_forwardWhat sequence of bases on one strand of DNA (reading in the 3′ to 5′ direction) is complementary to the sequence 5′ T-A-T-G-C-A-G 3′ on the other strand?arrow_forwardWhy are there nucleotides (A, T, G, and C) in the master mix? What are the other components of the master mix, and what are their functions?arrow_forward
- How are deoxyribonucleoside triphosphates (precursors of daughter DNA strands) and ribonucleoside triphosphates (precursors of RNA strand) differ from each other?arrow_forwardAn RNA molecule has the following percentages of bases: A = 27%, U = 38%, C=20%, G = 15%. (A) Is this RNA molecule single-stranded or double stranded? How can you tell? (B) What would be the percentage of each of the bases in the template strand of the DNA that contains the gene for this RNA?arrow_forwardHow does the double helix structure of DNA support its role in encoding the genome?arrow_forward
- What is the complete base composition of a double-stranded eukaryotic DNA that contains 22% guanine? Why is it necessary to specify that the DNA is double-stranded?arrow_forwardWhat is meant by the description "antiparellel" regarding the two strands that make up DNA?arrow_forwardWhat is the base sequence, specified in the 5′-to-3′ direction, for a segment of newly formed DNA if it was formed using the following template DNA segments? 3′ AATGC 5′ 5′ AATGC 3′ 3′ GCAGC 5′ 5′ GCAGC 3′arrow_forward
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