An RNA molecule has the following percentages of bases: A = 27%, U = 38%, C=20%, G= 15%. (A) Is this RNA molecule single-stranded or double stranded? How can you tell? (B) What would be the percentage of each of the bases in the template strand of the DNA that contains the gene for this RNA?

Why is it unfavorable for RNA molecules to adopt a double-helix structure similar to B-DNA?     Because it is entropically unfavorable     Because that would cause a steric clash between the sugars and nucleobases      Because that would cause a steric clash between the 2' OHs of the sugars and the phosphates     Because uracil can't form hydrogen bonds with any other nucleobases

Cystic fibrosis (CF) is an inherited disorder caused by different types of mutations, many of which prevent ions from moving across cell membranes. Normally there are channel proteins that allow passage of the ions, but in patients with one kind of CF these proteins seem odd. Closer examination shows that these proteins display the correct amino acid sequence. However, they fail to do their job. A) Given that the primary structure of the protein is correct, what can you infer about the DNA sequence for the gene coding this protein on this patient, is there a mutation? Explain. B) Why is the primary structure insufficient to guarantee the proper function of the protein?

The image below shows the base cytosine and a methylated form of cytosine that occurs frequently in the human genome. Use your knowledge of DNA structure to answer the following question: a) Does methylation of cytosine affect its ability to base-pair with guanine? Explain b) Could methylation of cytosine affect the binding of a protein that interacts with a C-G base-pair in the major groove? Explain your answer.

Which of the following recognizes the mRNA codon 5' - U A A - 3'?Question 29 options: A) a special termination tRNA B) a special termination amino acid C) a special termination protein D) Kozak's sequence E) aminoacyl tRNA synthetase

The characteristic way in which the DNA molecule is copied to form mRNA is most related to: a) the ability of RNA polymerase to match the shape of and the charges of the DNA monomers to the complementary mRNA nucleotide monomers, b) the ability of RNA polymerase to match the shape of and the charges of the DNA monomers to the anti-codons of tRNA, c) The interaction with the cell membrane, d) All of these e) None of these are correct

Sickle cell anemia is a widespread disease in many African countries and can be caused by a change in the amino acid sequence from glutamic acid to valine. A patient is diagnosed with the disease and a genetic fingerprint reveals the following DNA sequence for the gene: (a) (b) (c) (d) (e) Write down the mRNA sequence for the given DNA sense strand indicating the polarity. Derive the polypeptide from the mRNA molecule using the table of the genetic code (Table Q1 below) again indicating the polarity of the peptide chain. Indicate the position in the DNA molecule that could have caused the disease and write down all possible point mutations in the DNA sequence that could have caused it. [ The polypeptide chain is polymerized at the ribosomes using t-RNA molecules. Write down all possible t-RNA molecules with their anti-codons that are used to polymerize the amino acid VAL. Indicate the polarity. 3'-TAC TGA GCA AGA TTA CAT ACT-5' Explain what is meant by redundancy of the genetic code.…

You are characterizing a DNA-binding protein, and have used genetic experiments to identify a domain required for the interaction of the protein with DNA. Your secondary structure analysis software predicts that the domain forms a β helix, but you are unconvinced. What experiments could you perform to confirm the presence of a β helix in this region?

Which of the following single stranded DNA oligonucleotides alone would be expected to spontaneously form linear double stranded DNA molecules? A) 5'-ACGTTGCA-3' B) 5'-GGGGGGGC-3' C) 3'-GTCCCTAT-5 D) 3-CTAATTAG-5'    asap please

Write the base sequence in a complementary DNA segment if each original segment has the following base sequence: a.) 5'T T T T T T 3' b.) 5'C C C C C C C C C 3' c.) 5'A T G G C A 3' d.) 5'A T A T G C G C T A A A 3'