BIOLOGY
BIOLOGY
12th Edition
ISBN: 9781260169614
Author: Raven
Publisher: RENT MCG
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Chapter 43, Problem 4S
Summary Introduction

To determine: The evaluation of control of genes that controls the development and these regulate the expression of various parts of the genome.

Introduction: The genes are the functional unit of DNA. They possess some specific functions to perform. The different sets of the gene regulate the expression of different parts of the body.

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A graduate student performing studies on mutations in drosophila (fruit flies) discovered a strain of flies with a silent mutation in the gene controlling the shape of the wings. Further investigation has shown that this mutation is lethal in flies who are homozygote. Flies that are homozygote wild type or heterozygote can develop and are able to survive. What is a silent mutation (in your own words) and propose a hypothesis that could explain these observations using concepts learned. (a hypothesis is a proposed explanation based on an observation or observations)
What is a gene? Why are regulatory genes important to the evolutionary process? What is a mutation as defined in this course and readings. Are the end results of a mutation always "good" or always "bad"? Or is a mutation perhaps neither always good or always bad and could be "neutral or no effect" or "adaptive" in some situations? Does it depend on the gene, amino acid, protein, and case-by-case scenario? What genetic evidence suggests that humans are a part of a biological continuum with all life forms. Does the number of genes in a biological organism correlate, predict, or denote the complexity of the organism? Does the number of chromosomes in a biological organism correlate, predict, or denote the complexity of the organism?
Another way to study the role of proteins (e.g., transcription factors) that function in development is to microinject the mRNA that encodes a protein, or the purified protein itself, into an oocyte or embryo, and then determine how this affects the subsequent development of the embryo, larva, and adult. For example, if Bicoid protein is injected into the posterior region of an oocyte, the resulting embryo will develop into a larva that has anterior structures at both ends. Based on your understanding of the function of each developmental gene, what would be the predicted phenotype if the following proteins or mRNAs were injected into normal oocytes? A. Nanos mRNA injected into the anterior end of an oocyte B. Antp protein injected into the posterior end of an embryo C. Toll mRNA injected into the dorsal side of an early embryo
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