Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 42.4, Problem 3EQ
Summary Introduction
To determine: An experiment to test the hypothesis that acetylcholine is Loewi’s proposed vaghusstoff, using a heart (without its vagus nerve), some acetylcholine, and an acetylcholine receptor blocker.
Introduction: Otto Loewi, a German physiologist, through his experiments, showed that there is some non-electrical entity that is released into the surrounding of the electrically excited heart that results in the desired action on the heart muscles. Experimental studies by Loewi opened the doors for chemical neurotransmitter studies.
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parasympathetic nervous system ,True or False
Postganglionary neurons can stimulate the heart[ Select ]Preganglionary nerve fibers originate from the brain stem or from the sacral part of the spinal cord SantPreganglionary fibers are relatively long[ Select ]Preganglionary neuron emits acetylcholine[ Select ]Postganglionary neurons can stimulate skeletal muscle[ Select ]Postganglionary Neuron Emits Acetylcholine False
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lon channels
Greater response to norepinephrine
than epinephrine
Found at target organ in
parasympathetic pathways
Can inhibit cell activity
Activate CAMP
Greater response to epinephrine than
norepinephrine
Found in sympathetic and
parasympathetic pathways
Affect enzyme activity
Alpha receptors
Beta receptors
Nicotinic receptors
Muscarinic receptors
What do you think is the muscarinic receptor subtype that has a greater role in generating contractions in human detrusor smooth muscle (M2 or M3)? Propose further experiments that would support your answer.
Chapter 42 Solutions
Biology
Ch. 42.1 - Prob. 1CCCh. 42.2 - Prob. 1CSCh. 42.3 - Prob. 1CSCh. 42.3 - Prob. 2CSCh. 42.3 - Prob. 1CCCh. 42.3 - Prob. 2CCCh. 42.4 - What key prior observation led Loewi to develop...Ch. 42.4 - CoreSKILL The results of Loewis experiment...Ch. 42.4 - Prob. 3EQCh. 42 - Prob. 1TY
Ch. 42 - Prob. 2TYCh. 42 - The myelin sheath a. is produced by neurons in the...Ch. 42 - Prob. 4TYCh. 42 - Prob. 5TYCh. 42 - Which of the following contribute(s) to the...Ch. 42 - Prob. 7TYCh. 42 - Prob. 8TYCh. 42 - Prob. 9TYCh. 42 - Prob. 10TYCh. 42 - Prob. 1CQCh. 42 - Prob. 2CQCh. 42 - Prob. 3CQCh. 42 - Describe the difference between an electrical...Ch. 42 - Prob. 2COQ
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- fromthe Brain Stom 33. Acetylcholine (Ach) is the neurotransmitter at the neuro-muscular junction. The motor neuron releases Ach which diffuses across the synaptic cleft and binds to Ach- receptors (called nicotinic-receptors) on the post-synaptic muscle cell. Ach- receptor-blockers keep the Ach from binding to the nicotinic-receptors and therefore, block the action potential from occurring in the muscle-cell. This is the mode of inhibiting and paralyzing the skeletal muscles during surgery. Why might this be useful and necessary? a. without the Ach-receptor blocker the spinal-reflexes would cause the body to respond to the surgeons' knife. b. the ACh-receptor blocker is used to disable the motor cortex c. the ACh-receptor blocker completely inhibits the sympatheticand parasympathetic nervous systems, allowing the medical team to control all fundamental physiologic systems. d. the Ach-receptor blocker is used to disable the sensory cortex. piling the a Somatosons b. Sym ussystomarrow_forwardWhat do you think is the muscarinic receptor subtype that has a greater role in generating contractions in human detrusor smooth muscle (M2 or M3)?arrow_forwardRequired information ◄30s REFLEX ARC Skin Sensory receptor Stimulation of a sensory receptor results in the transmission of an afferent impulse along the axon of a sensory neuron. These axons end in the spinal cord. most cases, the impulse will then travel through an interneuron within the spinal cord to synapse with a motor neuron. 0:00 1:09 Sensory stimuli enter the spinal cord via Multiple Choice Sensory receptors Efferent axons Afferent axons Interneurons 1x 23arrow_forward
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