Prescott's Microbiology
11th Edition
ISBN: 9781260211887
Author: WILLEY, Sandman, Wood
Publisher: McGraw Hill
expand_more
expand_more
format_list_bulleted
Videos
Textbook Question
Chapter 42.1, Problem 1CC
What critical limiting factors are used in the production of penicillin? Why do you think the microbe must be stressed to produce high levels of drug?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
The type of antimicrobial drug that would be most likely to have toxic effects in
humans based on the premise of selective toxicity when treating microbial infection
would be a drug that
O 1) inhibits the synthesis of the cell wall
O 2) inhibits metabolic pathways
O 3) disrupts the cytoplasmic membrane
4) inhibits protein synthesis
5) All of the above have equal potential to be toxic
Some bacteria produce the enzyme penicillinase, which breaks the beta-lactam ring in the penicillin molecule and converts it into penicilloic acid, which is harmless to bacteria. This is an example of which of the following mechanisms of antibiotic resistance?
which option below is the answer?
Destruction or inactivation of the antibiotic by the microbe
Preventing penetration to the target site within the microbe
Alteration of the drug’s target site(s) within the microbe
None of the other four answers are correct
Rapid ejection (pumping) of the drug out of the microbial cell
Below, you can see a picture of an antimicrobial drug. Regarding semi-synthetic antimicrobial drug development to try to avoid development of antibiotic resistance, use 1 sentence to address what is the significance/value of the presence of the various R-groups (e.g. R4, R5, R6, etc.)?
Chapter 42 Solutions
Prescott's Microbiology
Ch. 42.1 - Why are the cells first fed lactose and then...Ch. 42.1 - What critical limiting factors are used in the...Ch. 42.1 - Prob. 2CCCh. 42.1 - What kinds of molecular changes result from...Ch. 42.1 - Prob. 4CCCh. 42.2 - Why is there interest in developing alternatives...Ch. 42.2 - What types of microbes are good candidates for the...Ch. 42.3 - What is the objective of the scale-up process and...Ch. 42.3 - What parameters can be monitored in a modern,...Ch. 42.3 - Which of the following are secondary metabolites:...
Ch. 42.4 - Why are modular genes particularly suitable as...Ch. 42.4 - Prob. 2MICh. 42.4 - Prob. 1CCCh. 42.4 - Prob. 2CCCh. 42.4 - What is metabolic engineering? Besides...Ch. 42.4 - What is high-throughput screening and why has it...Ch. 42.4 - Prob. 5CCCh. 42.5 - Prob. 1MICh. 42.5 - What is the Ti plasmid and how is it modified for...Ch. 42.5 - How is Bt toxin produced and why is it so widely...Ch. 42.5 - Prob. 3CCCh. 42.6 - Why are diatoms and magnetotactic bacteria of...Ch. 42.6 - Prob. 2CCCh. 42 - Prob. 1RCCh. 42 - Prob. 2RCCh. 42 - Prob. 3RCCh. 42 - Prob. 4RCCh. 42 - Prob. 5RCCh. 42 - Prob. 6RCCh. 42 - Prob. 7RCCh. 42 - Prob. 1ALCh. 42 - Prob. 2AL
Additional Science Textbook Solutions
Find more solutions based on key concepts
Identify each of the following reproductive barriers as prezygotic or postzygotic. a. One lilac species lives o...
Campbell Essential Biology with Physiology (5th Edition)
Jellyfish Lake, located on the Pacific island of Palau, is home to millions of jellyfish. Many years ago, sea l...
BIOLOGY:THE ESSENTIALS (LL) W/CONNECT
Match the people in column A to their contribution toward the advancement of microbiology, in column B. Column ...
Microbiology: An Introduction
What are the cervical and lumbar enlargements?
Principles of Anatomy and Physiology
Describe the evolution of mammals, tracing their synapsid lineage from early amniote ancestors to true mammals....
LooseLeaf for Integrated Principles of Zoology
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- What critical limiting factors are used in the production of penicillin?arrow_forwardWhich of the following types of antimicrobial drugs make microbes more susceptible to osmotic pressure? 1) drugs that inhibit nucleic acid synthesis O 2) drugs that inhibit metabolic pathways 3) drugs that inhibit cell wall synthesis 4) drugs that block a pathogen's recognition of its host 5) drugs that inhibit protein synthesisarrow_forwardHow can drug resistance in microorganisms be circumvented?arrow_forward
- What are some of the disadvantages of using natural penicillin for treatment of infections?arrow_forwardWith some level of toxic shock syndrome caused by the superantigen produced by Staphylococcus aureus, why the antibiotics are not effective after a certain point, even though the pathogen is susceptible to them?arrow_forwardWhat are two possible reasons for choosing a bacteriostatic treatment over a bactericidal one? Name the factors that can compromise the effectiveness of a disinfecting agentarrow_forward
- does a larger zone of inhibition always mean a drug is most effective? how do I know if s.aureus is a MRSA strain?arrow_forwardWhat is the main group of microorganisms producing the most antibiotics? Describe the biochemical characteristics of this microorganism and provide TWO (2) examples of antibiotics produced by these microbes.arrow_forwardChanges in the bacterial genome can lead to resistance to antimicrobialdrugs. what the different ways that these changes in the DNA occur?arrow_forward
- List four mechanisms that bacteria have developed through mutation to resist antimicrobial drugsarrow_forwardWe have many antimicrobial drugs to treat bacterial infections, but very few for viruses. Why is it so difficult to treat viral infections? Hint: What would the targets for the drugs be?arrow_forwardBroad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment. Which statement best explains why a broad spectrum drug might be an undesirable treatment choice? Broad-spectrum antimicrobials are usually toxic to the host cells. Broad-spectrum antimicrobials only work if they are used shortly after the infection begins. Broad-spectrum antimicrobials may kill much of the normal microbiota. Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth. Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
USMLE-Rx Antimicrobial Therapy; Author: USMLE-Rx;https://www.youtube.com/watch?v=Pka1Ynlrqtw;License: Standard Youtube License