Campbell Biology
Campbell Biology
12th Edition
ISBN: 9780135188743
Author: Urry
Publisher: PEARSON
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Chapter 42, Problem 8TYU

DRAW IT Plot blood pressure against time for one cardiac cycle in humans, drawing separate lines for the pressure in the aorta, the left ventricle, and the right ventricle. Below the time axis, add a vertical arrow pointing to the time when you expect a peak in atrial blood pressure.

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The events of the cardiac cycle cause cyclical changes in left ventricular pressure and volume over time. Another way to represent these events is with a pressure-volume loop, as shown below. Drag the labels from the left into the appropriate boxes on the pressure- volume loop to demonstrate your understanding of the cardiac cycle. Aortic valve closure AV valve opening Systolic pressure Isovolumetric relaxation Isovolumetric contraction 120 Diastolic pressure Ventricular filling 80 End-diastolic volume Ventricular ejection 40 AV valve closure End-systolic volume Aortic valve opening 60 120 LV volume (mL) O McGraw-Hill Education Reset LV pressure (mm Hg)
Plot blood pressure against time for one cardiac cycle in humans, drawing separate lines for the pressure in the aorta, the left ventricle, and the right ventricle. Below the time axis, add a vertical arrow pointing to the time when you expect a peak in atrial blood pressure.
The pressure in the aorta changes throughout the cardiac cycle. During systole, as the heart contracts, the outflux of blood into the aorta causes an increase in pressure, whereas during diastole the pressure decreases as the heart relaxes. A simple model for the aortic pressure waveform is given by the Windkessel effect described by the image below. In this model, the heart is considered a pressure generating pump which is directly connected to an elastic compartment (the aorta), which in turn is connected to a rigid set of peripheral vessels (the hose of the firefighter). 5 Pump Heart Air Windkessel Elastic arteries In order to find the aortic pressure waveform from the Windkessel model, a mass balance formulation around the aorta must be formulated. Coming into the aorta from the heart we have the flowrate Q(t). According to conservation of mass, this inflow rate Q(t) must be equal to the outflow rate into the peripheral vessels and the change in volume of the aorta. To find these…
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