Biochemistry: Concepts and Connections
Biochemistry: Concepts and Connections
1st Edition
ISBN: 9780321839923
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
bartleby

Concept explainers

bartleby

Videos

Question
Book Icon
Chapter 4, Problem 1P
Interpretation Introduction

Interpretation:

The following blanks should be filled with suitable substances as mentioned below:

    ……….. Adenosine …….. Uridine
    ……….. Cytidine 5'-monophospahe …….. Deoxycytidine 5'triphosphate
    ……….. Guanine ……… Deoxyuridine
    ……….. Thymine ………. Guanosine 5'-diphosphate
    ……….. Deoxyguanosine ………. Thymidine triphosphate
  1. A nucleobase
  2. A ribonucleoside
  3. A ribonucleotide
  4. A deoxyribonucleoside
  5. A deoxyribonucleotide
  6. A dinucleotide

Concept Introduction:

A nucleobase is a biological compound. It is basically as nitrogen containing base. They form nucleosides and nucleotides which are made up of nucleic acid. The only difference between a nucleoside and nucleotide is presence of phosphate group in the nucleotides. The common between them is a nitrogenous base and a five-carbon sugar. If a nucleoside contain ribose as a component then it is known as ribonucleoside, where ribose is carbohydrate (pentose monosaccharide) with molecular formula C5H10O5. Similarly, ribonucleoside is ribose containing nucleotide. In ribose, if a hydroxyl group is replaced by hydrogen, it become deoxyribose. Thus, deoxyribonucleoside and deoxyribonucleotide are nucleoside and nucleotide with deoxyribose as a component. If there are two units of each of the nitrogenous base, sugar and phosphate group present in a compound it is known as dinucleotide.

Answer:

    (b) A ribonucleoside-Adenosine (b) A ribonucleoside -Uridine
    (c) A ribonucleotide-Cytidine 5'-monophosphate

    (e) A deoxyribonucleotide-

    Deoxycytidine 5'triphosphate

    (a) A nucleobase-Guanine (d) A deoxyribonucleoside-Deoxyuridine
    (a) A nucleobase-Thymine (c) A ribonucleotide- Guanosine 5'-diphosphate
    (d) A deoxyribonucleoside-Deoxyguanosine (e) A deoxyribonucleotide-Thymidine triphosphate

Expert Solution & Answer
Check Mark

Explanation of Solution

The structure of Adenosine and uridine are as follows:

Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  1Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  2

Adenosine Uridine

Both are ribonucleoside as they contain ribofuranose attached by glycosidic bond to the purine nucleoside.

The structure of Cytidine 5'-monophosphate and guanosine 5'-diphosphate are as follows:

Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  3Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  4

Cytidine 5'-monophosphate Guanosine 5'-diphosphate

The nucleoside cytidine and guanine are attached to phosphoric acid through ester linkage, thus, they form a nucleotide. There is also a pentose sugar ribose hence, they are classified as a ribonucleotide. There is one phosphate group in cytidine 5'-monophosphate and two phosphate groups in guanosine 5'-diphosphate.

Guanine and thiamine both are nucleobase, as they are nitrogen containing bases. They are found in nucleic acids DNA and RNA.

The structures are as follows:

Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  5Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  6

Guanine Thymine

Deoxyguanosine and deoxyuridine are deoxyribonucleoside as they contain deoxyribose without phosphate group.

The structures are as follows:

Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  7Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  8

Deoxyguanosine Deoxyuridine

Deoxycytidine 5'triphosphate and thymidine triphosphate are deoxyribonucleotide as they contain deoxyribose with phosphate group attached to nucleoside.

The structures are as follows:

Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  9Biochemistry: Concepts and Connections, Chapter 4, Problem 1P , additional homework tip  10

Deoxycytidine 5'triphosphate Thymidine triphosphate

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!
Knowledge Booster
Background pattern image
Biochemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Recommended textbooks for you
Text book image
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Text book image
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Text book image
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Text book image
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Text book image
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Text book image
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON
Macromolecules | Classes and Functions; Author: 2 Minute Classroom;https://www.youtube.com/watch?v=V5hhrDFo8Vk;License: Standard youtube license