Biology
Biology
12th Edition
ISBN: 9780078024269
Author: Sylvia Mader, Michael Windelspecht
Publisher: McGraw-Hill Education
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Chapter 3.1, Problem 2CYP

Explain why the substitution of a carboxyl group for a hydroxyl group in a biomolecule would change the molecule’s function.

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In studying a particular biomolecule (a protein, nucleic acid, carbohydrate, or lipid) in the laboratory, the biochemist first needs to separate it from other biomolecules in the sample—that is, to purify it. Specific purification techniques are described later in the book. However, by looking at the monomeric subunits of a biomolecule, you should have some ideas about the characteristics of the molecule that would allow you to separate it from other molecules. For example, how would you separate (a) amino acids from fatty acids and (b) nucleotides from glucose?
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