Essential Cell Biology
Essential Cell Biology
4th Edition
ISBN: 9780815344544
Author: Keith Roberts, Karen Hopkin, Alexander D Johnson, Martin Raff, Dennis Bray, Bruce Alberts, Julian Lewis, Peter Walter
Publisher: TAYLOR
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Chapter 3, Problem 5Q
Summary Introduction

To assume: How the speed of carbonic anhydrase is limited.

Introduction:

Carbonic anhydrase is a catalytic enzyme that catalyzes the conversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction also co-ordinates relatively slow in the absence of catalyst. The reaction: CO2+H2OCarbonicanhydraseHCO3+H+ is the major reaction for an efficient transport of CO2 which occurs in the tissue of lungs. In this reaction, the diffusion rate of the substrates, limits the catalytic rate of the enzyme. The catalytic rate of the enzyme ranges between 104 and 106.

Summary Introduction

To draw: A diagram to show 107 fold acceleration of the reaction.

Introduction:

Carbonic anhydrase is a catalytic enzyme that catalyzes the conversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction also co-ordinates relatively slow in the absence of catalyst. The reaction: CO2+H2OCarbonicanhydraseHCO3+H+ is the major reaction for an efficient transport of CO2 which occurs in the tissue of lungs. In this reaction, the diffusion rate of the substrates, limits the catalytic rate of the enzyme. The catalytic rate of the enzyme ranges between 104 and 106.

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