Organic Chemistry
9th Edition
ISBN: 9781305080485
Author: John E. McMurry
Publisher: Cengage Learning
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Chapter 29.SE, Problem 27MP
Interpretation Introduction
Interpretation:
A mechanism for the conversion of acetoacetate to acetyl CoA.
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The enzyme that catalyzes reaction below can be classified as:
NAD*
NADH + H*
Но-
H-Ć-
Н—с—н
H-
malate
dehydrogenase
Oxaloacetate
Malate
NADH + H+
NAD+
H₂O
FADH₂
COASH + NAD+
X
FAD
CO₂ + NADH + H+
H₂O
GTP +
COASH
COASH
GDP +
Pi
NAD+
NADH + H+
+ CO₂
•COASH + NAD+
NADH + H+ + CO₂
ter 18
em 18.18
Part A
What coenzyme picks up hydrogen when a carbon-oxygen double bond is formed?
Express your answers as a chemical expression.
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Chapter 29 Solutions
Organic Chemistry
Ch. 29.1 - Prob. 1PCh. 29.3 - Write the equations for the remaining passages of...Ch. 29.3 - Prob. 3PCh. 29.4 - Write a mechanism for the dehydration reaction of...Ch. 29.4 - Evidence for the role of acetate in fatty-acid...Ch. 29.4 - Does the reduction of acetoacetyl ACP in step 6...Ch. 29.5 - Prob. 7PCh. 29.5 - Look at the entire glycolysis pathway, and make a...Ch. 29.6 - Prob. 9PCh. 29.7 - Prob. 10P
Ch. 29.7 - Write mechanisms for step 2 of the citric acid...Ch. 29.7 - Prob. 12PCh. 29.8 - Prob. 13PCh. 29.9 - Write all the steps in the transamination reaction...Ch. 29.9 - What -keto acid is formed on transamination of...Ch. 29.9 - Prob. 16PCh. 29.SE - Prob. 17VCCh. 29.SE - Identify the following intermediate in the citric...Ch. 29.SE - The following compound is an intermediate in the...Ch. 29.SE - Prob. 20VCCh. 29.SE - In the pentose phosphate pathway for degrading...Ch. 29.SE - Prob. 22MPCh. 29.SE - One of the steps in the pentose phosphate pathway...Ch. 29.SE - One of the steps in the pentose phosphate pathway...Ch. 29.SE - Prob. 25MPCh. 29.SE - Prob. 26MPCh. 29.SE - Prob. 27MPCh. 29.SE - Prob. 28MPCh. 29.SE - Prob. 29MPCh. 29.SE - Prob. 30MPCh. 29.SE - Prob. 31MPCh. 29.SE - Prob. 32APCh. 29.SE - Prob. 33APCh. 29.SE - Prob. 34APCh. 29.SE - Prob. 35APCh. 29.SE - Prob. 36APCh. 29.SE - Prob. 37APCh. 29.SE - Prob. 38APCh. 29.SE - Prob. 39APCh. 29.SE - Prob. 40APCh. 29.SE - Prob. 41APCh. 29.SE - Prob. 42APCh. 29.SE - Prob. 43APCh. 29.SE - Prob. 44APCh. 29.SE - Prob. 45APCh. 29.SE - Prob. 46APCh. 29.SE - Prob. 47APCh. 29.SE - Prob. 48APCh. 29.SE - Prob. 49APCh. 29.SE - Prob. 50APCh. 29.SE - In glycerol metabolism, the oxidation of...Ch. 29.SE - Prob. 52APCh. 29.SE - Prob. 53APCh. 29.SE - Prob. 54APCh. 29.SE - In step 7 of fatty-acid biosynthesis (Figure...Ch. 29.SE - Prob. 56AP
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- Refer to the following reaction. The substrate of this reaction is called through a mechanism called "Feed Forward Activation". (A) Phosphoenolpyruvate, Fructose 1,6-bisphosphate Lactate, NADH OPO₂²- ADP ATP J = 4 O H₂C H₂C 2-phosphoglycerate, AMP Glyceraldehyde 3-phosphate, ATP and the enzyme is activated by high conc. ofarrow_forwardChoose a different family of natural products derived from the acetate pathway and propose how such pathway would overlap with the cannabinoid?arrow_forwardWhat amino acid is obtained from the reductive amination of the following metabolic intermediates in a cell by reductive amination?arrow_forward
- Modify the given molecule to show the product of the oxidation reaction using NAD+ as the oxidizing agent. Include the appropriate hydrogen atoms and charges. OH O .lari. -CH₂- NAD+ Select Draw Rings More / ||| ||| C 0 H 44 H 4 Erase +NADH- ho given molecule to show the product of the oxidation reaction using FAD as the oxidizing agent. Include thearrow_forwardWhat is the product of the following reaction sequence: HN H₂N HN HO B transaminase C Product NH OH Show Transcribed Text choose between A,B,D,E NOT C D HO E NHarrow_forwardA portion of the citric acid cycle is shown below. What are the identities of A and B? citrate → A→isocitrate → B A = cis-aconitate; B = a-ketoglutarate A = malate; B = fumarate A = cis-aconitate; B = oxaloacetate A = a-ketoglutarate; B = succinate A = succinate; B = a-ketoglutaratearrow_forward
- Nonearrow_forwardOne of the steps that occur during the synthesis of ketone bodies is shown below. OH D-beta-hydroxybutyrate Dehydrógenase .coo coo0 H3C cooo Нас acetoacetate D-beta-hydroxybutyrate Does this process require FAD or NAD*, FADH2 or NADH as the reactant coenzyme? Explain your answer in a few words.arrow_forwardMost fatty acids have an even number of carbons and, therefore, are completely metabolized to acetyl-CoA. A fatty acid with an odd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA. The following two reactions convert propionyl-CoA into succinyl-CoA, a citric acid cycle intermediate, so it can be further metabolized. Each of the reactions requires a coenzyme. Identify the coenzyme for each step. From what vitamins are the coenzymes derived?arrow_forward
- Most fatty acids have an even number of carbons and, therefore, are completely metabolized to acetyl-CoA. A fatty acid with an odd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA. The following two reactions convert propionyl-CoA into succinyl-CoA, a citric acid cycle intermediate, so it can be further metabolized. Each of the reactions requires a coenzyme. Identify the coenzyme for each step. From what vitamins are the coenzymes derived?arrow_forwardUnder conditions of starvation, acetyl-CoA, instead of being degraded in the citric acid cycle, is converted to acetone and 3-hydroxybutyrate, compounds called ketone bodies that the brain can use as a temporary fuel. Show how the ketone bodies are formed.arrow_forwardCan you help to solve this?arrow_forward
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