Introduction To General, Organic, And Biochemistry
12th Edition
ISBN: 9781337571357
Author: Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 28, Problem 28P
Interpretation Introduction
Interpretation:
The importance of HMG-CoA reductase in the synthesis of cholesterol is to be interpreted.
Concept introduction:
The synthesis of cholesterol begins with the sequential condensation of three acetyl CoA molecules.
Expert Solution & Answer
Trending nowThis is a popular solution!
Students have asked these similar questions
Fatty acids and triglycerides are an important source of nutrition and a dense form
of stored energy. Digestion of fats yields more energy per gram than digestion of
carbohydrates.
Each turn on the B-oxidation spiral results in the formation of a new acetyl COA
molecule. This molecule can then be used to generate more energy in
A) fatty acid synthesis
B) ketolysis
C) glycolysis
D) tricarboxylic acid cycle
E) oxidative phosphorylation
The glycolysis pathway is shown. Place the enzymes used in each of the ten labeled steps of the pathway. Be sure to scroll
down completely until pyruvate is formed.
triosephosphate isomerase
phosphofructokinase-1
glucose-6-phosphate
fructose-6-phosphate
fructose-1,6-biphosphate
ADP
ATP
ADP
hexokinase
ATP
glucose
dihydroxyacetonephosphate
phosphohexose isomerase
Answer Bank
What am I doing wrong?
aldolase
glyceraldehyde-3-phosphate
glyceraldehyde-3-phosphate
dehydrogenase
phosphoglycerate kinase
phosphoglycerate mutase
enolase
pyruvate kinase
NAD* + HOPO₂²
NADH+H*
1,3-bisphosphoglycerate
ADP
ATP
3-phosphoglycerate
Z-phosphoglycerate
phosphoenolpyruvate
ADP
ATP
pyruvate
The glycolysis pathway is shown. Place the enzymes used in each of the ten labeled steps of the pathway. Be sure to scroll
down completely until pyruvate is formed.
glucose-6-phosphate
fructose-6-phosphate
fructose-1,6-biphosphate
ADP
ATP
ADP
ATP
glucose
dihydroxyacetonephosphate
glyceraldehyde-3-phosphate
1,3-bisphosphoglycerate
ADP
ATP
3-phosphoglycerate
2-phosphoglycerate
phosphoenolpyruvate
ADP
ATP
pyruvate
Answer Bank
phosphoglycerate mutase
hexokinase
phosphohexose isomerase
triosephosphate isomerase
phosphofructokinase-1
pyruvate kinase
phosphoglycerate kinase
aldolase
enolase
glyceraldehyde-3-phosphate
dehydrogenase
NAD + HOPO3²-
NADH+H*
Chapter 28 Solutions
Introduction To General, Organic, And Biochemistry
Ch. 28.1 - Prob. 28.1QCCh. 28.2 - Prob. 28.2QCCh. 28.3 - Prob. 28.3QCCh. 28.4 - Prob. 28.4QCCh. 28.5 - Prob. 28.5QCCh. 28 - Prob. 1PCh. 28 - Prob. 2PCh. 28 - Prob. 3PCh. 28 - Prob. 4PCh. 28 - Prob. 5P
Ch. 28 - Prob. 6PCh. 28 - Prob. 7PCh. 28 - Prob. 8PCh. 28 - Prob. 9PCh. 28 - Prob. 10PCh. 28 - Prob. 11PCh. 28 - Prob. 12PCh. 28 - Prob. 13PCh. 28 - Prob. 14PCh. 28 - Prob. 15PCh. 28 - Prob. 16PCh. 28 - Prob. 17PCh. 28 - Prob. 18PCh. 28 - Prob. 19PCh. 28 - Prob. 20PCh. 28 - Prob. 21PCh. 28 - Which of these fatty acids can be synthesized by...Ch. 28 - Prob. 23PCh. 28 - Prob. 24PCh. 28 - Prob. 25PCh. 28 - Prob. 26PCh. 28 - Prob. 27PCh. 28 - Prob. 28PCh. 28 - Prob. 29PCh. 28 - Prob. 30PCh. 28 - Prob. 31PCh. 28 - Prob. 32PCh. 28 - Prob. 33PCh. 28 - Prob. 34PCh. 28 - Prob. 35PCh. 28 - Prob. 36PCh. 28 - Prob. 37PCh. 28 - Prob. 38PCh. 28 - (Chemical Connections 28B ) Why is exercise doubly...Ch. 28 - Prob. 40PCh. 28 - Prob. 41PCh. 28 - Prob. 42PCh. 28 - Prob. 43PCh. 28 - (Chemical Connections 28D ) What is the result of...Ch. 28 - Prob. 45PCh. 28 - Prob. 46PCh. 28 - Prob. 47PCh. 28 - Prob. 48PCh. 28 - Prob. 49PCh. 28 - Prob. 50PCh. 28 - Prob. 51PCh. 28 - Prob. 52PCh. 28 - Prob. 53PCh. 28 - Prob. 54PCh. 28 - Prob. 55PCh. 28 - Prob. 56PCh. 28 - Prob. 57PCh. 28 - Prob. 58PCh. 28 - Prob. 59PCh. 28 - 29-60 How does the energy source differ in...Ch. 28 - Prob. 61PCh. 28 - A vegan diet is one that excludes all animal...Ch. 28 - Prob. 63PCh. 28 - Prob. 64PCh. 28 - Prob. 65PCh. 28 - Prob. 66PCh. 28 - Prob. 67P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Similar questions
- Consider this chemical reaction. What chemical is the oxidizing agent? COO™ HIC-H HIC-H FAD FADH₂ COO™ succinate FADH2 succinate FAD fumarate succinate dehydrogenase COO™ H-C -H COO fumaratearrow_forwardWhat class of enzymes to these two belong to?arrow_forwardIn the citric acid cycle, a - ketoglutarate dehydrogenase catalyzes the reaction from a - ketoglutarate to Succinyl CoA. Given this reaction, calculate for the enthalpy of formation of the product using (a) Hess's Law, (b) standard enthalpies of formation and (c) mean bond enthalpies. Show your complete solution. COA-S OOC CH2 CH2 + NAD++ COA + CO2 + NADH CH2 a-ketoglutarate CH2 dehydrogenase COO a-ketoglutarate COO Succinyl CoAarrow_forward
- Kinases are enzymes that catalyze the addition (or removal) of a phosphate group to ( or from) a substance. ATP is also involved. How many kinases are in glycolysis? Name them.arrow_forwardWhy is the conversion of lactic acid from the blood into glucose in the liver in an organism’s best interest?arrow_forwardChemistry What is the main aspect that the enzymes succinyl-CoA synthetase, pyruvate kinase, and phosphoglycerate kinase have in common?arrow_forward
- All of the following enzymes regulate glycolysis except? Phosphofructokinase Phosphoglycerate kinase Hexokinase Pyruvate kinase Question 6 ( Which of the following enzymes is regulated by the concentration of glucose 6-phosphate? Hexokinase Phosphoglycerate kinase Pyruvate kinase Phosphofructokinasearrow_forwardChemistry the image below shows the citric acid cycle. The image below shows the citric acid cycle. Reaction 5 is the substrate-level phosphorylation. Select the correct statement about this reaction Acetyl-CoA Condensation CH₂-C-S-CoA H₂O CoA-SH citrate CH₂-COO™ synthase 011000 HO-C-COO™ (2a CH₂-COO Dehydration Dehydrogenation Citrate Citric acid H₂O aconitase cycle NADH malate Coo- dehydro- genase HO-CH Malate COO™ Hydration fumarase H₂O COO™ Fumarate CH HC coo Dehydrogenation CH₂ CH₂-COO Oxaloacetate FADH₂ succinate dehydrogenase CH₂-COO CH₂ COO- Succinate succinyl-CoA synthetase Succinyl-CoA CH-COO™ c-coo c-c0011 aconitase CO₂ cis-Aconitate H₂O (2b Hydration Isocitrate Oxidative decarboxylation a-ketoglutarate dehydrogenase complex CH₂-COO™ COA-SH CH₂ CoA-SH GTP GDP C-5-CoA (ATP) (ADP) + P₁ Substrate-level Oxidative decarboxylation phosphorylation Figure 16-7 Lehninger Principles of Biochemistry, Fifth Edition 2008 W.H. Freeman and Company O The reaction is NADH dependent O A…arrow_forwardThe enzyme that catalyzes reaction below can be classified as: NAD* NADH + H* Но- H-Ć- Н—с—н H- malate dehydrogenase Oxaloacetate Malatearrow_forward
- Mark any/all processes that are reductions. O FADH2 → FAD O hydrogenation of fats FAD FADH2 NAD* NADH NADH NAD*arrow_forwardThe rate-limiting step is a metabolic pathway is the slowest step which determines the overall rate of the other reactions in the pathway. In glycolysis, the rate limiting step is a phosphorylation reaction where phosphofructokinase (PFK-1) catalyzes the reaction fructose-6-bisphosphate -> fructose-1,6-bisphosphate, the same step in gluconeogenesis. Select one: The statement is FALSE. The statement is TRUE.arrow_forwardOne of the steps that occur during the synthesis of ketone bodies is shown below. OH D-beta-hydroxybutyrate Dehydrógenase .coo coo0 H3C cooo Нас acetoacetate D-beta-hydroxybutyrate Does this process require FAD or NAD*, FADH2 or NADH as the reactant coenzyme? Explain your answer in a few words.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningGeneral, Organic, and Biological ChemistryChemistryISBN:9781285853918Author:H. Stephen StokerPublisher:Cengage LearningOrganic And Biological ChemistryChemistryISBN:9781305081079Author:STOKER, H. Stephen (howard Stephen)Publisher:Cengage Learning,
- Chemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage Learning
Introduction to General, Organic and Biochemistry
Chemistry
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Cengage Learning
General, Organic, and Biological Chemistry
Chemistry
ISBN:9781285853918
Author:H. Stephen Stoker
Publisher:Cengage Learning
Organic And Biological Chemistry
Chemistry
ISBN:9781305081079
Author:STOKER, H. Stephen (howard Stephen)
Publisher:Cengage Learning,
Chemistry for Today: General, Organic, and Bioche...
Chemistry
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Cengage Learning
DIGESTER-35 | VITAMINS AND THEIR RELATED COENZYMES| GPAT | NIPER | PHARMACIST| DI; Author: GPAT DISCUSSION CENTER;https://www.youtube.com/watch?v=CGrdNYmho0s;License: Standard YouTube License, CC-BY