The mechanism for the conversion of 2,2-dimethylpropan-1-ol to 2-methylbut-2-ene should be described. Concept introduction: The preparation of alkene is the type of elimination reaction. The E1 is the unimolecular elimination reaction, the order of the reaction is one. In this reaction, loss of leaving groups to form a carbocation as intermediate in the presence of heat. The rearrangement of carbocation takes place. The E2 is the bimolecular elimination reaction, the order of the reaction is two. In this reaction, base extracts the proton adjacent to the leaving group in the presence of strong heat. A nucleophile is the Lewis base that donates a pair of an electron to form a covalent bond with the electrophile. An electrophile is the Lewis acid that accepts the electron to form a bond with the nucleophile. The good leaving groups are the weak base. They can be an anion or neutral molecule.

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Chapter 27, Problem 28E

Interpretation Introduction

Interpretation:

The mechanism for the conversion of 2,2-dimethylpropan-1-ol to 2-methylbut-2-ene should be described.

Concept introduction:

The preparation of alkene is the type of elimination reaction.

The E1 is the unimolecular elimination reaction, the order of the reaction is one. In this reaction, loss of leaving groups to form a carbocation as intermediate in the presence of heat. The rearrangement of carbocation takes place.

The E2 is the bimolecular elimination reaction, the order of the reaction is two. In this reaction, base extracts the proton adjacent to the leaving group in the presence of strong heat.

A nucleophile is the Lewis base that donates a pair of an electron to form a covalent bond with the electrophile. An electrophile is the Lewis acid that accepts the electron to form a bond with the nucleophile.

The good leaving groups are the weak base. They can be an anion or neutral molecule.

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