Concept explainers
Case summary:
A 23-year-old woman has her first prenatal examination. She is 4 1/4 months pregnant. Her VDRL results showed negative. The woman returns to her physician complaining of a labial lesion of a few days' duration. A biopsy is negative for malignancy, and herpes test results shows negative. The woman returns to her physician because the labial lesion continues to cause some discomfort. The baby's father has multiple penile lesions and a generalized body rash. The woman delivers her baby. Her RPR is 32, and the infant's is 128. The woman takes her infant to a pediatrician because the baby is lethargic. She has been told that the infant is healthy and need not be worried. The baby's father has a persistent body rash and plantar and palmar rashes. The infant becomes acutely ill with pneumonia and is hospitalized. The admitting physician finds the signs of osteochondritis.
Characters of the case
Symptoms: Labial lesion; the father has multiple penile lesions and body rash.
Diagnosis: VDRL negative, no malignancy, herpes test shows negative.
About the disease:
Syphilisis caused byTreponema pallidum. Congenital syphilis can be transmitted to unborn fetus through placenta and affect the mental development and also could lead to death. Antibiotics benzathine penicillin treatment during the first two trimesters can prevent congenital syphilis.
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Microbiology: An Introduction (13th Edition)
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