Becker's World of the Cell (9th Edition)
Becker's World of the Cell (9th Edition)
9th Edition
ISBN: 9780321934925
Author: Jeff Hardin, Gregory Paul Bertoni
Publisher: PEARSON
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Chapter 25, Problem 25.6PS

Meiotic Mistakes. Infants born with Patau syndrome have an extra copy of chromosome 13, which leads to developmental abnormalities such as cleft lip and palate, small eyes, and extra fingers and toes. Another type of genetic disorder, Turner syndrome, results from the presence of only one sex chromosome—an X chromosome. Individuals born with one X chromosome are females exhibiting few noticeable defects until puberty, when they fail to develop normal breasts and internal sexual organs. Describe the meiotic events that could lead to the birth of an individual with either Patau syndrome or Turner syndrome.

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Familial Down syndrome is similar to primary Down syndrome in that it is caused by trisomy 21. However, in familial Down syndrome, all or part of the third copy of chromosome 21 has translocated onto another autosome, typically chromosome 14. In cases of familial Down syndrome, one of the parents of the affected child is often a carrier of a translocated chromosome. The translocation carrier parent does not have Down syndrome because he or she has a total of two copies of chromosome 21. Suppose that a woman is a translocation carrier of chromosome 21 on chromosome 14. She conceives six zygotes with a normal man who carries no aneuploidies. Match the description of the chromosomes inherited by each zygote with the viability of the zygote. Viable normal, or translocation carrier Viable, with Down syndrome Inviable Answer Bank two normal copies of 21, one normal copy of 14 two normal copies of 21, two normal copies of 14 one 21 to 14 translocation, one normal copy of 21, two normal copies…
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