Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 25, Problem 23P
Interpretation Introduction

(a) Interpretation:

If a gene underwent a mutation that changed a GAA codon to UAA codon, the amino acid encoded by the original triplet should be determined.

Concept Introduction:

A mutation is referred to as nonsense mutation where the codon for a specific amino acid has been changed to stop the codon and this leads to the termination of the translation process of the polypeptide chain.

Interpretation Introduction

(b) Interpretation:

A transfer RNA (tRNA) anticodon which can translate the nonsense UAA triplet should be identified.

Concept Introduction:

A mutation is referred to as nonsense mutation where the codon for a specific amino acid has been changed to stop the codon and this leads to the termination of the translation process of the polypeptide chain.

Interpretation Introduction

(c) Interpretation:

The other amino acids which could be encoded by the mutant transfer RNA should be determined.

Concept Introduction:

A mutation is referred to as nonsense mutation where the codon for a specific amino acid has been changed to stop the codon and this leads to the termination of the translation process of the polypeptide chain.

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Mitochondrial mutations; Author: Useful Genetics;https://www.youtube.com/watch?v=GvgXe-3RJeU;License: CC-BY