Anatomy & Physiology (6th Edition)
6th Edition
ISBN: 9780134156415
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Textbook Question
Chapter 24.4, Problem 18CYU
Which of the pressures that determine NFP is regulated by both intrinsic and extrinsic controls of GFR?
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Which of the pressures that determine NFP is regulated by both intrinsic and extrinsic controls of GFR?
Extrinsic and intrinsic controls of GFR serve two different purposes. What are they?
Describe the mechanisms of extrinsic regulation of GFR, and their physiological role.
Chapter 24 Solutions
Anatomy & Physiology (6th Edition)
Ch. 24.1 - Prob. 1CYUCh. 24.1 - From inside to outside, list the three layers of...Ch. 24.1 - The lumen of the ureter is continuous with a space...Ch. 24.2 - Name the tubular components of a nephron in the...Ch. 24.2 - What are the structural differences between...Ch. 24.2 - What type of capillaries are the glomerular...Ch. 24.2 - Prob. 19CYUCh. 24.3 - In the kidneys, tubular secretion of a substance...Ch. 24.4 - Extrinsic and intrinsic controls of GFR serve two...Ch. 24.4 - Calculate net filtration pressure given the...
Ch. 24.4 - Which of the pressures that determine NFP is...Ch. 24.5 - In which part of the nephron does most...Ch. 24.5 - How does the movement of Na+ drive the...Ch. 24.5 - MAKING conections Primary and secondary active...Ch. 24.6 - List several substances that are secreted into the...Ch. 24.7 - Describe the special characteristics of the...Ch. 24.7 - Under what conditions is ADH released from the...Ch. 24.8 - What would you expect the normal clearance value...Ch. 24.8 - What are the three major nitrogenous wastes...Ch. 24.9 - A kidney stone blocking a ureter would interfere...Ch. 24.9 - What is the trigone of the bladder, and which...Ch. 24.9 - Name the three regions of the male urethra.Ch. 24.9 - How does the detrusor respond to increased firing...Ch. 24.9 - MAKING connections Compare the structure and...Ch. 24 - The lowest blood concentration of nitrogenous...Ch. 24 - The glomerular capillaries differ from other...Ch. 24 - Damage to the renal medulla would interfere first...Ch. 24 - Which is reabsorbed by the proximal convoluted...Ch. 24 - Glucose is not normally found in the urine because...Ch. 24 - Filtration at the glomerulus is inversely related...Ch. 24 - Tubular reabsorption (a) of glucose and many other...Ch. 24 - If a freshly voided urine sample contains...Ch. 24 - Conditions such as diabetes mellitus and...Ch. 24 - Which of the following is/are true about ADH? (a)...Ch. 24 - What is the importance of the perirenal fat...Ch. 24 - Trace the pathway a creatinine molecule takes from...Ch. 24 - Explain the important differences between blood...Ch. 24 - Describe the mechanisms that contribute to renal...Ch. 24 - Prob. 5SAQCh. 24 - Describe what is involved in active and passive...Ch. 24 - Explain how the peritubular capillaries are...Ch. 24 - Explain the process and purpose of tubular...Ch. 24 - How does aldosterone modify the chemical...Ch. 24 - Explain why the filtrate becomes hypotonic as it...Ch. 24 - How does urinary bladder anatomy support its...Ch. 24 - Define micturition and describe the micturition...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...Ch. 24 - Lets return to Kyle Boulard, whom we met in the...
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- How does sympathetic stimulation change GFR? What receptors and NTs are involved?arrow_forwardExplain the autoregulatory mechanism of GFR.arrow_forwardState the two methods of intrinsic control used to regulate GFR. Choose one of the methods and explain in details how it specifically helps regulate the GFR when blood pressure changes.arrow_forward
- Describe how each of the following functions in the extrinsic control of GFR: renin-angiotensin mechanism, natriuretic peptides, and sympathetic adrenergic activityarrow_forwardIf the rate of urine formation is 2 ml/min, the urine inulin concentration is 25 mg/ml, and the plasma inulin concentration 0.5 mg/ml, then the GFR is 6.25 mL/min None of the choices are correct. (c) 0.04 mL/min D) 100 mL/min E) more data is needed to calculate the GFRarrow_forwardEstimate the GFR in a 48-year-old woman who weighs 60 kg using the Cockcroft-Gault equation (in mL/min). Her serum creatinine level is 2.5 mg/dL (round to the next full number; no decimal places). Please help with this question and show the work. Thanksarrow_forward
- What does lab tes GFR 25mL/min means. What are the pathophysiology of GFR?arrow_forwardExplain the role each of the following plays in GFR regulation: Intrinsic control: Renal autoregulation Myogenic mechanism Tubuloglomerular feedback mechanism Extrinsic control: neural and hormonal mechanism Sympathetic nervous system controls Renin-Angiotensin-Aldosterone mechanismarrow_forwardSuppose a tumor is pressing on and obstructing the right ureter. What effect might this have on CHP and thus on NFP in the right kidney? Would the left kidney also be affected?arrow_forward
- calculate the filtered load of a substance that is dissolved in plasma given the plasma concentration of 0.065mg/ml and a GFR of 125 ml/min. consider that 30% of the substance is bound to plasma proteins. Round the answer to one decimal placearrow_forwardWhat two quantities make up “H1 excretion”? Why can this term beequated with “contribution of new HCO32 to the plasma”?arrow_forwardThe Na+-glucose transporters SGLT2 and SGLT1 are located at different levels of the kidney proximal tubule to minimize spillover of the glucose into the urine (See diagram attached) a) Consider the Na+-glucose coupling ratios for SGLT2 and SGLT1. Why would localization of SGLT2 in the early proximal tubule and SGLT1 in the late proximal tubule be advantageous? b) The Michaelis constant (Km) for the SGLT2 and SGLT1 transporters are 2 mM and 0.5 mM, respectively. Is SGLT2 or SGLT1 the higher affinity Na+-glucose transporter? d) Dapagliflozin is an SGLT1 inhibitor and commonly prescribed to treat type 2 diabetes. Why would this be of benefit to a diabetes patient?arrow_forward
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