Fundamentals of Biochemistry: Life at the Molecular Level
Fundamentals of Biochemistry: Life at the Molecular Level
5th Edition
ISBN: 9781118918401
Author: Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher: WILEY
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Chapter 24, Problem 32CQ
Summary Introduction

To compare: The overall backbone length for a PNA and a DNA molecule.

Concept introduction: PNAs also known as peptide nucleic acids are the molecules that mimic DNA in structure, but contain pseudo-peptide backbone. These molecules are artificially created for forming stable structural-duplex with DNA and RNA molecules. Structural adaptability, specificity, and affinity of PNA molecules made their existence as a powerful molecular tool for binding with nucleic acids.

Summary Introduction

To explain:  The reason why the PNA and DNA can form base-paired duplexes.

Concept introduction: PNAs also known as peptide nucleic acids are the molecules that mimic DNA in structure, but contain pseudo-peptide backbone. These molecules are artificially created for forming stable structural duplex with DNA and RNA molecules. Structural adaptability, specificity, and affinity of PNA molecules made their existence as a powerful molecular tool for binding with nucleic acids.

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Macromolecules | Classes and Functions; Author: 2 Minute Classroom;https://www.youtube.com/watch?v=V5hhrDFo8Vk;License: Standard youtube license