Concept explainers
Place the following events of glucose catabolism in the correct order, placing a 1 by the first event, a 2 by the second, and so forth.
a. _________ Electrons are passed between electron carriers in the inner mitochondrial membrane, and hydrogen ions are pumped into the intermembrane space.
b. __________ ATP is generated in the cytosol by substrate-level phosphorylation; NADH is generated as well.
c. ________ Hydrogen ions pass through the channel of ATP synthase and ATP is released from the enzyme.
d. ________ Acetyl-CoA is combined with oxaloacetate to form citrate.
e. ________ ATP is consumed to split glucose into two three-carbon compounds.
f. ________ Pyruvate loses a carbon, forming acetyl-CoA, carbon dioxide, and NADH.
g. _______ Citrate undergoes a series of
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Human Anatomy & Physiology (2nd Edition)
- b) Place a 'Yes' or a 'No' in the appropriate boxes that correspond to each listed feature of cellular respiration. You may need to state 'Yes' or 'No' in more than one box in a particular row in some cases. Cellular Respiration Feature Involved in aerobic respiration Occurs in the mitochondrial matrix Pyruvate molecules are produced Acetyl COA combines with a 4 carbon molecule Electrons are passed between protein carriers ATP is produced NAD+ gains hydrogen FADH₂ loses hydrogen Glycolysis Yes / No Krebs Cycle Yes / No Electron Transport chain Yes / Noarrow_forwardConcerning the process of the aerobic fate of glucose oxidation, which of the following statements is false? a. The spontaneous movement of protons is coupled to the unfavorable movement of electrons through the electron transport chain b. Pyruvate is recognized by a pyruvate/proton symporter for movement into the matrix of the mitochondria c. The matrix of the mitochondria is more negative than the inner membrane space d. Mitochondria contain two membranes, only the inner mitochondrial membrane is highly selective for what passes across it e. The movement of protons through ATP synthase drive the production of ATParrow_forwardWhich of the following statements is true about the citric acid cycle a. The Citric Acid Cycle is an 8-step cycle that produces the most electron carrier molecules throughout the process of cellular respiration. b. In Citric Acid Cycle, both the acetyl group and coenzyme A of Acetyl CoA are combined to oxaloacetate. c. In Citric Acid Cycle, glucose is only partially broken down and there are still remnants of glucose after this process. d. The ATP produced during this process is via oxidative phosphorylationarrow_forward
- The oxidative phase of the pentose phosphate pathway produces which of the following (note - select all that apply)? A. ATP B. Glucose-6-phosphate C. NADPH D. Ribose-5-phosphatearrow_forwardConsider a 24:1 △cis-9 fatty acid in the mitochondrion. For each fatty acid given, determine the following. Gross ATP from b-oxidation cycles Gross ATP from acetyl CoA produced Gross ATP from conversion of propionyl CoA (if applicable) Total number of ATP deducted Total net ATParrow_forwardWhich of the following dehydrogenases delivers electrons to directly to UQ in the electron transport pathway from the intermembrane space side of the inner mitochondrial membrane? a. succinate dehydrogenase b. acyl CoA dehydrogenase c. creatine kinase dehydrogenase d. glycerol-3-phosphate dehydrogenasearrow_forward
- In the 1930s, some physicians prescribed low doses of a compound called dinitrophenol (DNP) to help patients lose weight. This unsafe method was abandoned after some patients died. DNP uncouples the chemiosmotic machinery by making the lipid bilayer of the inner mitochondrial membrane leaky to H+ . Explain how this could cause weight loss and death.arrow_forwardWhich of the following statements are TRUE?Multiple answers are accepted for this question a .Two molecules of CO2 are produced each time a molecule of Acetyl-CoA is oxidized. b. During the first turn of the TCA Cycle the carbon atoms of Acetyl-CoA become CO2. c. The number of molecules of ATP that can be produced in the Citric Acid Cycle by substrate level phosphorylation of ADP from two molecules of Acetyl-CoA is 30. d. Fumarate contains a trans double bond. The cis isomer of Fumarate is Maleate which cannot serve as carbon source for a cell. e. Lack of O2 would decrease the rate of the Citric Acid Cycle in red blood cells. f. If a potent inhibitor of Succinyl-CoA Synthetaseis is applied to liver cells both energy production and synthesis of carbohydrate would be affected. g. The overall chemical changes that occur during one complete turn of the Citric Acid Cycle is the complete oxidation of one molecule of Acetyl-CoA plus the production of two molecules of CO2 plus the…arrow_forwardWhich of the following statements is NOT true about the electron transport chain (ETC) and oxidative phosphorylation? (Only one answer applies) A. Oxidative phosphorylation requires the enzyme complexes to be soluble in the mitochondrial matrix. B. If the proton gradient is too high, electrons will not move through the ETC. C. The movement of electrons down the ETC only happens if protons are pumped out of the mitochondrial matrix. D. Oxidative phosphorylation requires the mitochondrial intermembrane space to be more positively charged than the matrix. E. The free energy of the proton gradient can be used to create high energy bonds.arrow_forward
- Pyruvate is transformed to Acetyl-CoA in one of two ways: a. in the cytoplasm by an oxidative carboxylation process b.Through the mitochondrial matrix's oxidative decarboxylation mechanism C. In the mitochondrial matrix, via a dehydration process d.Through the liver's glucose-6-phosphatasearrow_forwardFill in the missing numbers to complete the following statement regarding the pentose phosphate pathway. The oxidation of 6 mol of glucose by the pentose phosphate pathway may result in the production of ______ mol of pentose, ______ mol of NADPH and ______ mol of CO2.arrow_forwardWhich of the following statements about cellular respiration is TRUE in eukaryotes? A. For every molecule of NADH oxidized in the electron transport chain, 1 molecule of ATP is produced. B. ATP synthase harnesses the flow of protons (hydrogen ions = H+) from the mitochondrial matrix to the intermembrane space to produce ATP. C. ATP synthase transduces the flow of protons (hydrogen ions = H+) from the intermembrane space to the mitochondrial matrix into kinetic (mechanical) energy D. H2O is the final electron acceptor in the electron transport chain, being oxidized to O2 and H+. E. All of the above are truearrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning