Concept explainers
Interpretation:
In the nitration of phenol (
Concept introduction:
The substituent on the benzene ring prior to substitution dictates the regiochemistry of the reaction. Some substituents are designated as ortho/para directors because they lead to product mixtures consisting primarily of the ortho- and para-disubstituted products. Other substituents are designated as meta directors because they favor the formation of the meta-disubstituted product. The results from nitration reactions are summarized in Table 23-1:
In the nitration of phenol (
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Organic Chemistry: Principles and Mechanisms (Second Edition)
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