Chapter 22, Problem 22.50P

Interpretation Introduction

(a)

Interpretation:

The curved-arrow mechanism for the formation of $\text{butyryl-ACP}$ from the reaction between $trans\text{-crotonyl-ACP}$ and $\text{NADPH}$ is to be stated.

Concept introduction:

The reagent $\text{NADPH}$ is a reducing agent. It is a selective reagent and reduces only the double bond of the $\text{α,β-}$ unsaturated carbonyl group. The reagent $\text{NADPH}$ is acidic and donates the proton to form ${\text{NADP}}^{\text{+}}$.

Interpretation Introduction

(b)

Interpretation:

The reason as to why the reaction between $trans\text{-crotonyl-ACP}$ and $\text{NADPH}$ for the formation of $\text{butyryl-ACP}$ is an example of a conjugate addition is to be stated.

Concept introduction:

The reagent, $\text{NADPH}$ is a reducing agent. It is a selective reagent and reduces only the double bond of the $\text{α,β-}$ unsaturated carbonyl group. The reagent, $\text{NADPH}$ is acidic and donates the proton to form ${\text{NADP}}^{\text{+}}$.

Interpretation Introduction

(c)

Interpretation:

Whether the reaction between $\text{NADPD}$ and $trans\text{-crotonyl-ACP}$ is a conjugate syn-addition or trans-addition reaction is to be identified with reason.

Concept introduction:

The reagent, $\text{NADPD}$ is a reducing agent. It is a selective reagent and reduces only the double bond of the $\text{α,β-}$ unsaturated carbonyl group. The reagent, $\text{NADPH}$ is acidic and donates the proton to form ${\text{NADP}}^{\text{+}}$.