Chapter 21.7, Problem 14P

Interpretation Introduction

(a)

Interpretation: The product that is formed by the reaction of $2-\text{bromopentan}-3-\text{one}$ with ${\text{Li}}_{\text{2}}{\text{O}}_{\text{3}}$, $\text{LiBr}$, DMF is to be drawn.

Concept introduction: The bimolecular elimination reaction that favours the removal of a HX substituent from an alkyl halide that needs a base to remove $\text{H}$ from carbon adjacent to the leaving group that in turn forms a double bond is termed ${\text{E}}^2$ elimination reaction.

Interpretation Introduction

(b)

Interpretation: The product that is formed by the reaction of $2-\text{bromopentan}-3-\text{one}$ with ${\text{CH}}_{\text{3}}{\text{CH}}_{\text{2}}{\text{NH}}_{\text{2}}$ is to be drawn.

Concept introduction: The substitution reaction involves the replacement of one functional group by other functional group. In nucleophilic substitution an electron rich species attack the species that is deficient in electrons. The electrophile and the leaving group together form a substrate. The nucleophile attacks over the substrate and there occurs the removal of leaving group from the substrate.

The nucleophilic reaction that consists of bimolecular as well as bond-making and bond-breaking steps is termed as ${\text{S}}_{\text{N}}\text{2}$ reactions. This is a one-step reaction in which both nucleophile and substrate participate in the rate determining step.

Interpretation Introduction

(c)

Interpretation: The product that is formed by the reaction of $2-\text{bromopentan}-3-\text{one}$ with ${\text{CH}}_{\text{3}}\text{SH}$ is to be drawn.

Concept introduction: The substitution reaction involves the replacement of one functional group by other functional group. In nucleophilic substitution an electron rich species attack the species that is deficient in electrons. The electrophile and the leaving group together form a substrate. The nucleophile attacks over the substrate and there occurs the removal of leaving group from the substrate.

The nucleophilic reaction that consists of bimolecular as well as bond-making and bond-breaking steps is termed as ${\text{S}}_{\text{N}}\text{2}$ reactions. This is a one-step reaction in which both nucleophile and substrate participate in the rate determining step.