Essentials of Genetics (9th Edition) - Standalone book
Essentials of Genetics (9th Edition) - Standalone book
9th Edition
ISBN: 9780134047799
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino
Publisher: PEARSON
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Chapter 21, Problem 9PDQ

What kind of heritability estimates (broad sense or narrow sense) are obtained from human twin studies?

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What kind of heritability estimates (broad sense or narrow sense) are obtained from human twin studies?
Why are monozygotic twins who are reared apart so useful in the calculation of heritability? What assumption is being made about their respective environment?
ADHD is a highly heritable trait with published broad sense heritability estimates in the range of 0.6- 0.9. Larsson et al. 2014 (doi: 10.1017/S0033291713002493 ) reported the concordance values shown in the table below for pairs of monozygotic (MZ) or dizygotic (DZ) twins with data for male and female pairs shown separately, using data from the Swedish twin register (59,000 twin pairs, born between 1959 and 2001). Male MZ twins Male DZ twins Female MZ twins Female DZ twins 56% 16% 37% 13% Based on the data in this table, does ADHD appear to be more heritable in males or females? Provide one sentence of rationale to support your answer.
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