Biology
12th Edition
ISBN: 9780134813448
Author: Audesirk, Teresa, Gerald, Byers, Bruce E.
Publisher: Pearson,
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Textbook Question
Chapter 2.1, Problem 4TC
In addition to lower brain activity, what other problem has occurred in the Alzheimer’s victim’s brain as shown by the images in Fig. E2 2?
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What biological markers have been found that might indicate the presence of Alzheimer's disease in a human being?
Link: https://doi.org/10.1186/s12868-022-00692-1
A. In the effect of mitoxantrone on histopathological changes in the brain section of the results section the authors wrote “In Fig. 4, the demyelination of (A-C) the cerebellum and (F-H) brain stem was evaluated using LFB staining and median scored 2.5 in both sedentary and exercised untreated EAE rats indicating extensive demyelination.” Why was demyelination evaluated in this study?
B. In the effect of mitoxantrone on histopathological changes in the brain section of the results section the authors wrote “Post-administration of mitoxantrone to sedentary and exercised groups smaller patches of demyelination with microcyst formation and lymphocytic infiltrates were seen; and bare unmyelinated axons were fewer (Figs. 3D, E, I, J and 4D, E, I, J).” Based on this quote, what is mitoxantrone doing exactly/directly?
Describe two abnormalities seen in the brain of Alzheimerdisease patients.
Chapter 2 Solutions
Biology
Ch. 2.1 - What is the mass number of hydrogen? Of helium?Ch. 2.1 - Unstable Atoms Unleashed Because exposure to...Ch. 2.1 - Prob. 2TCCh. 2.1 - What causes the coals of a campfire to glow?Ch. 2.1 - In addition to lower brain activity, what other...Ch. 2.1 - define clement and atom?Ch. 2.1 - Prob. 2CYLCh. 2.1 - explain atomic number and mass number?Ch. 2.1 - explain radioactivity and its dangers and...Ch. 2.1 - describe electron shells?
Ch. 2.2 - At a physical exam, Thomas, a sedentary...Ch. 2.2 - Prob. 1CYLCh. 2.2 - Prob. 2CYLCh. 2.2 - explain atomic number and mass number?Ch. 2.3 - The slap of a belly flop provides firsthand...Ch. 2.3 - Prob. 1TCCh. 2.3 - Predict how a drop of water on an oil-coated...Ch. 2.3 - Prob. 3TCCh. 2.3 - Prob. 1CYLCh. 2.3 - Prob. 2CYLCh. 2.3 - explain atomic number and mass number?Ch. 2.3 - Prob. 1CTCh. 2 - Which of the following is false? a. An dement is...Ch. 2 - Prob. 2MCCh. 2 - Isotopes are defined as a. atoms of the same...Ch. 2 - Prob. 4MCCh. 2 - Prob. 5MCCh. 2 - An atom consists of an atomic nucleus composed of...Ch. 2 - An atom that has lost or gained one or more...Ch. 2 - Prob. 3FIBCh. 2 - Prob. 4FIBCh. 2 - Water is described as __________ because each...Ch. 2 - Prob. 1RQCh. 2 - Distinguish between atoms and molecules and among...Ch. 2 - Prob. 3RQCh. 2 - Prob. 4RQCh. 2 - Prob. 5RQCh. 2 - Prob. 6RQCh. 2 - Prob. 7RQCh. 2 - Detergents help clean by dispersing fats and oils...Ch. 2 - Prob. 2ACCh. 2 - Prob. 3AC
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- Exactly what does it mean to say that a person is in the "preclinical phase" of Alzheimer's disease? What implications does this have for the progression of the illness?arrow_forwardIf an accurate diagnostic test for Alzheimer’s disease is developed and there is no treatment for the disease, should the test be made available?arrow_forwardWhy do you think Alzheimer'sdisease can not be cured through the intake of neurotransmitter?arrow_forward
- list and briefly explain one cause of neuron degeneration in Alzheimer's diseasearrow_forward1) Please explain the likelihood of Susan and Lisa developing Schizophrenia and Alzheimer’s. A) Susan tells you that her twin brother has just been diagnosed with schizophrenia. She wants to know her risk factors for developing the disorder. B) Lisa, a 55-year-old high school teacher, recently discovered that her mother has been diagnosed with Alzheimer’s disease at the age of 78. Alzheimer’s disease is a progressive brain disorder that impairs memory, thinking skills, and the ability to carry out simple tasks. Given her mother’s diagnosis and her own increasing forgetfulness, Lisa is concerned about her risk of developing Alzheimer’s disease and seeks counseling for guidance.arrow_forwardDoes Alzheimer’s disease always have an autosomal dominant inheritance pattern? Provide evidence that supports this claimarrow_forward
- Contrast early and late-onset Alzheimer disease. What are three genes associated with the inheritance of susceptibility to early-lonset Alzheimer disease?arrow_forward2(3) Finds at least two types of drugs used to treat these three diseases. -Alzheimer's -Amnesia -Hypotonia a)What are the different types of drugs used to treat people with these diseases or conditions? b) What is the difference between these drugs? c) Can vitamins or natural supplements have an effect on the nervous system? d) How do these drugs affect the brain and nervous system? e)Are drugs still used in the treatment and prevention of neurological diseases or conditions?arrow_forwardWhich of the following statements best describes the appearance of amyloid plaques and neurofibrillary tangles in Alzheimer's Disease? Amyloid plaques do first appear in neocortical structures spreading to basal ganglia structures, while neurofibrillary tangles are first found in locus coeruleus spreading to the neocortex. Amyloid plaques and neurofibrillary tangles do first appear in basal ganglia structures and then spread progressively to neocortical structures. Amyloid plaques and neurofibrillary tangles are evenly spread throughout basal ganglia, diencephalic and neocortical structures. Amyloid plaques and neurofibrillary tangles do first appear in neocortical structures and then spread progressively to basal ganglia structures.arrow_forward
- All of the following true about amnesia, EXCEPT: A) Anterograde Amnesia is defined as the inability to form new memories after brain trauma O B) Retrograde amnesia is defined as memory loss for things prior to the brain trauma OO Dissociative Amnesia has both retrograde amnesia and global cognitive deficits O D) Amresia is adly defined as a serious loss of memory or ability to lear. O E) Transient Amnesia is a sudden and short, but can be hallmarked by both Retrograde and Anterograde Anesiaarrow_forwardС. Currently, about how many people in the United States over the age of 65 suffer from Alzheimer's disease?arrow_forwardWhat does the fact that rotenone appears to increase the susceptibility to Parkinson disease indicate about the etiology of Parkinson disease?arrow_forward
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