Human Anatomy
9th Edition
ISBN: 9780135168059
Author: Marieb, Elaine Nicpon, Brady, Patricia, Mallatt, Jon
Publisher: Pearson Education, Inc.,
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 2, Problem 6CRCAQ
The drug vinblastine is used in cancer therapy to stop the runaway division of cancer cells. Vinblastine inhibits the assembly and growth of microtubules. Explain how the action of this drug prevents mitosis (refer to Figure 2.17).
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Which is true for cancer cells:
1) Cell death occurs after a determined number of cell divisions
2) Contact with other cells reduces chance of cell division
3) Cell division occurs in the presence of stop signals.
Oncologists (cancer doctors) frequently measure the mitotic index of tumor cells when they are removed via surgery or biopsy. What do you think is the value of finding out the mitotic index of these cells?
The drug vinblastine is used in cancer therapy to stop the runaway division of cancer cells. Vinblastine inhibits the assembly and growth of microtubules. Explain how the action of this drug prevents mitosis (refer to Figure 2.17).
Chapter 2 Solutions
Human Anatomy
Ch. 2 - What are the three general regions of a cell?Ch. 2 - What types of macromolecules compose the plasma...Ch. 2 - By what process does water enter and leave the...Ch. 2 - Which transport process carries large...Ch. 2 - Which cellular organelles are involved with...Ch. 2 - Which organelle produces the energy needed for...Ch. 2 - Which organelle would be prevalent in a cell that...Ch. 2 - Which cytoskeletal element functions to resist...Ch. 2 - What does the nucleolus produce?Ch. 2 - Which cytoplasmic organelle is continuous with the...
Ch. 2 - How does the appearance of extended chromatin...Ch. 2 - In which phase of the cell life cycle does the...Ch. 2 - Prob. 13CYUCh. 2 - Which cellular structures would be abundant in...Ch. 2 - Which organelles would be abundant in cells that...Ch. 2 - According to which aging theory presented here can...Ch. 2 - The endocytotic process in which particulate...Ch. 2 - The nuclear substance composed of histone proteins...Ch. 2 - Final preparations for cell division are made...Ch. 2 - Prob. 4RQCh. 2 - Identify the cell structure or organelle described...Ch. 2 - Prob. 6RQCh. 2 - The trans face of the Golgi apparatus (a) is its...Ch. 2 - Prob. 8RQCh. 2 - Name the appropriate stage of mitosis (prophase,...Ch. 2 - Name the cytoskeletal element (actin...Ch. 2 - Prob. 11RQCh. 2 - Which of these processes involves specific...Ch. 2 - List all the cytoplasmic organelles that are...Ch. 2 - Martin missed a point on his anatomy test because...Ch. 2 - In this chapter, we claimed that mitochondria are...Ch. 2 - Define chromosome, then compare the arrangement of...Ch. 2 - Prob. 17RQCh. 2 - Use the analogy of the cell as a manufacturing...Ch. 2 - Prob. 1CRCAQCh. 2 - Kareem had a nervous habit of chewing on the inner...Ch. 2 - The normal function of one tumor-suppressor gene...Ch. 2 - In their anatomy labs, many students are exposed...Ch. 2 - The sedative phenobarbital is a lipid-soluble...Ch. 2 - The drug vinblastine is used in cancer therapy to...Ch. 2 - Use the word roots listed at the start of Chapter...
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Why is cell furrowing important in cell division? If cytokinesis did not occur, what would be the end result?arrow_forward(b) What is the role of microtubules in mitosis? How does vincristine contribute to the cell cycle arrest of cancer cells? Explain. Microtubulesarrow_forwardIn the absence of cdc25 cells would not be able to undergo mitosis. True or False?arrow_forward
- The phases of mitosis are shown in Figure 6.4. Mitosis is the type of nuclear division that occurs when an animal or plant grows larger and when injury heals. Two daughter cells result because there is only one round of division, and it keeps the chromosome number constant (same as the parent cell). The prophase cell in Figure 6.4 has the same number of chromosomes as the telophase nuclei in Figure 6.4. Explain the different appearance of the chromosomes.arrow_forwardThe anticancer drug paclitaxel (Taxol), derived from the Pacific Yew, has many effects on mitosis. One of its most powerful effects is that it prevents disassembly of the mitotic spindle, which prevents spindle fibers from shortening. Which phase of mitosis would this directly affect? Why would this stop cell division overall and lead to cell death?arrow_forwardCancer is a disease in which cells exhibit uncontrolled cell division. Drugs used in the study of microtubules are also used in the treatment of cancer. Why are drugs that disrupt microtubules more useful in the treatment of cancer than are drugs used to disrupt microfilaments? What is the name of the category of these drugs that describes their function?arrow_forward
- The drug chloral hydrate prevents elongation of microtubules by preventing the addition of new subunits to the growing end. During which stage of mitosis would chloral hydrate be most harmful?arrow_forwardThe drug taxol is extracted from the bark of yew trees. It binds tightly to microtubules and stabilizes them. When added to cells, it causes much of the free tubulin to assemble into microtubules. Taxol can be used as an anticancer drug. At the molecular level, what does the drug prevent? At the cellular level, what part of cell division does it prevent? Be specific.arrow_forwardChemotherapy drugs such as vincristine and colchicines disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly. Explicitly referring to Mitosis, explain what mitotic structure is targeted by these drugs, and what effect would this have on cell division?arrow_forward
- Explain the property that prevents normal cells from becoming cancerous.arrow_forwardMany cancer drugs stop cell division. List several mechanisms that could hinder cell division?arrow_forwardWhen some cancer cells produce growth factors that stimulate their own division leading to continuous self- stimulation for cell division it is referred to as a) TNF tumor necrosis factor b) AGS autocrine growth stimulationarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
The Cell Cycle and its Regulation; Author: Professor Dave Explains;https://www.youtube.com/watch?v=eqJqhA8HSJ0;License: Standard YouTube License, CC-BY
Cell Division - Mitosis and Meiosis - GCSE Biology (9-1); Author: Mr Exham Biology;https://www.youtube.com/watch?v=w7vp_uRA8kw;License: Standard YouTube License, CC-BY