Fundamentals of Biostatistics
8th Edition
ISBN: 9781305268920
Author: Bernard Rosner
Publisher: Cengage Learning
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Chapter 2, Problem 33P
Activated-protein-C (APC) resistance is a serum marker that has been associated with thrombosis (the formation of blood clots often leading to heart attacks) among adults. A study assessed this risk factor among adolescents. To assess the reproducibility of the assay, a split-sample technique was used in which a blood sample was provided by 10 people; each sample was split into two aliquots (sub-samples), and each aliquot was assessed separately. Table 2.19 gives the results.
Table 2.19 APC resistance split-samples data
To assess the variability of the assay, the investigators need to compute the coefficient of variation. Compute the coefficient of variation (CV) for each subject by obtaining the mean and standard deviation over the 2 replicates for each subject.
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two groups. The first group participated in a weekly aquarobic exercise program for 8 weeks; the second group served as a control. Several pieces of data were collected from the individuals, including their total cholesterol (mg).
Determine if there is a significant difference in the mean cholesterol for the two groups (aquarobic & control) at the start of the study using a significance level of 0.10.
Difference
Sample Diff. Std. Error
df
Aquarobic - Control
2.698
7.3227 65.6844
• What hypotheses should be tested? Make sure to select the hypotheses which are written with notation consistent with the type of samples selected.
H.: µd
= l2 H.: µ1 = µ2 H.:µd
H.: Hd > 0 Ha: H1 # H2 Ha:µ1 > µ2 Ha:Hd < 0 Ha:H1 < µs Ha: Hd # 0
= 0 H,:µ1
0 H.: µ1 = µ2 H.: µd
•…
A study was undertaken to investigate the effectiveness of an aquarobic exercise program for patients with osteoarthritis. A convenience sample of 70 individuals with arthritis was selected, and each person was randomly assigned to one of two groups. The first group participated in a weekly aquarobic exercise program for 8 weeks; the second group served as a control. Several pieces of data were collected from the individuals, including their total cholesterol (mg).
Determine if there is a significant difference in the mean cholesterol for the two groups (aquarobic & control) at the start of the study using a significance level of 0.01.
Difference
Sample Diff.
Std. Error
df
Aquarobic - Control
-13.9045
6.8214
67.8635
What hypotheses should be tested? Make sure to select the hypotheses which are written with notation consistent with the type of samples selected.
Ho:μd=0Ho:μd=0Ha:μd>0Ha:μd>0
Ho:μd=0Ho:μd=0Ha:μd<0Ha:μd<0
Ho:μ1=μ2Ho:μ1=μ2Ha:μ1<μ2Ha:μ1<μ2…
Chapter 2 Solutions
Fundamentals of Biostatistics
Ch. 2.6 - When is it appropriate to use the arithmetic mean...Ch. 2.6 - How does the geometric mean differ from the...Ch. 2.6 - What is the difference between the standard...Ch. 2.8 - What is a stem-and-leaf plot? How does it differ...Ch. 2.8 - Prob. B.2RECh. 2.8 - Consider the stem-and-leaf plot in Figure 2.6. Is...Ch. 2.8 - What is a box plot? What additional information...Ch. 2 - The data in Table 2.13 are a sample from a larger...Ch. 2 - The data in Table 2.13 are a sample from a larger...Ch. 2 - It is of clinical interest to know if the duration...
Ch. 2 - Suppose the scale for a data set is changed by...Ch. 2 - Suppose the scale for a data set is changed by...Ch. 2 - Suppose the scale for a data set is changed by...Ch. 2 - Suppose the scale for a data set is changed by...Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - A man runs 1 mile approximately once per weekend....Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - The data in Table 2.15 are a sample of cholesterol...Ch. 2 - In an experiment that examined the effect of body...Ch. 2 - In an experiment that examined the effect of body...Ch. 2 - Table 2.17 Format for FEV.DAT The data in Table...Ch. 2 - Forced expiratory volume (FEV) is an index of...Ch. 2 - Forced expiratory volume (FEV) is an index of...Ch. 2 - Prob. 26PCh. 2 - The food-frequency questionnaire (FFQ) is an...Ch. 2 - In Section 2.9, we described Data Set LEAD.DAT (at...Ch. 2 - In Section 2.9, we described Data Set LEAD.DAT (at...Ch. 2 - Activated-protein-C (APC) resistance is a serum...Ch. 2 - Activated-protein-C (APC) resistance is a serum...Ch. 2 - A study was conducted to demonstrate that soy...Ch. 2 - A study was conducted to demonstrate that soy...Ch. 2 - A study was conducted to demonstrate that soy...Ch. 2 - Prob. 38PCh. 2 - In Section 2.10, we described Data Set BONEDEN.DAT...Ch. 2 - What impression do you have of the relationship...Ch. 2 - In Section 2.10, we described Data Set BONEDEN.DAT...Ch. 2 - In Section 2.10, we described Data Set BONEDEN.DAT...Ch. 2 - Prob. 43PCh. 2 - Prob. 44PCh. 2 - Prob. 45PCh. 2 - Answer Problems 2.382.40 for BMD for the femoral...Ch. 2 - The Left Ventricular Mass lndex (LVMI) is a...Ch. 2 - Prob. 48PCh. 2 - Prob. 49PCh. 2 - The Left Ventricular Mass lndex (LVMI) is a...
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