Activation of Gemcitabine should be identified. Concept introduction: Activation of Gemcitabine indicates the phosphorylation of the drug by an enzyme dCK whereas on eliminating the toxic nature of the drug the deamination of the amino group of the gemcitabine takes place by CDA and thus the drug can be eliminated.

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Answer 1

Question

Chapter 19, Problem 27P

Interpretation Introduction

Interpretation:

Activation of Gemcitabine should be identified.

Concept introduction:

Activation of Gemcitabine indicates the phosphorylation of the drug by an enzyme dCK whereas on eliminating the toxic nature of the drug the deamination of the amino group of the gemcitabine takes place by CDA and thus the drug can be eliminated.

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Answer 2

Question

Chapter 19, Problem 27P

Interpretation Introduction

Interpretation:

Activation of Gemcitabine should be identified.

Concept introduction:

Activation of Gemcitabine indicates the phosphorylation of the drug by an enzyme dCK whereas on eliminating the toxic nature of the drug the deamination of the amino group of the gemcitabine takes place by CDA and thus the drug can be eliminated.

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Answer 3

Question

Chapter 19, Problem 27P

Interpretation Introduction

Interpretation:

Activation of Gemcitabine should be identified.

Concept introduction:

Activation of Gemcitabine indicates the phosphorylation of the drug by an enzyme dCK whereas on eliminating the toxic nature of the drug the deamination of the amino group of the gemcitabine takes place by CDA and thus the drug can be eliminated.

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Answer 4

Question

Chapter 19, Problem 27P

Interpretation Introduction

Interpretation:

Activation of Gemcitabine should be identified.

Concept introduction:

Activation of Gemcitabine indicates the phosphorylation of the drug by an enzyme dCK whereas on eliminating the toxic nature of the drug the deamination of the amino group of the gemcitabine takes place by CDA and thus the drug can be eliminated.

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Answer 5

Chapter 19, Problem 27P

Interpretation Introduction

Interpretation:

Activation of Gemcitabine should be identified.

Concept introduction:

Activation of Gemcitabine indicates the phosphorylation of the drug by an enzyme dCK whereas on eliminating the toxic nature of the drug the deamination of the amino group of the gemcitabine takes place by CDA and thus the drug can be eliminated.

Answer 6

Chapter 19, Problem 27P

Interpretation Introduction

Interpretation:

Activation of Gemcitabine should be identified.

Concept introduction:

Activation of Gemcitabine indicates the phosphorylation of the drug by an enzyme dCK whereas on eliminating the toxic nature of the drug the deamination of the amino group of the gemcitabine takes place by CDA and thus the drug can be eliminated.

Answer 7

Chapter 19, Problem 27P

Interpretation Introduction

Interpretation:

Activation of Gemcitabine should be identified.

Concept introduction:

Activation of Gemcitabine indicates the phosphorylation of the drug by an enzyme dCK whereas on eliminating the toxic nature of the drug the deamination of the amino group of the gemcitabine takes place by CDA and thus the drug can be eliminated.

Answer 8

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Answer 9

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Answer 10

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Answer 11

Ch. 19 - Prob. 1P Ch. 19 - Prob. 2P Ch. 19 - Predict the effects of the following compounds on...Ch. 19 - Prob. 4P Ch. 19 - Prob. 5P Ch. 19 - Prob. 6P Ch. 19 - Prob. 7P Ch. 19 - A classic way to isolate thymidylate...Ch. 19 - Prob. 9P Ch. 19 - Prob. 10P

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