Chapter 18.8, Problem 17P

(a)

Interpretation Introduction

Interpretation: It should be described that how the given compound is prepared from cyclohexanone using an enamine intermediate.

Concept Introduction: To increase the carbon chain, substituting an alkyl group on alpha carbon of a carbonyl group is called alkylation.

Alkylation is carried out by reaction of a ketone with a secondary amine in the presence of an acid to form an enamine and then adding an appropriate alkyl halide. The alkylation is a ${\text{S}}_{\text{N}}\text{2}$ reaction. The alkylation works best with a primary alkyl halide.

Acylation is carried out by reaction of a ketone with a secondary amine in the presence of an acid to form an enamine and then adding an appropriate acyl halide.  The acylation is an addition reaction.

(b)

Interpretation Introduction

Interpretation: It should be described that how the given compound is prepared from cyclohexanone using an enamine intermediate.

Concept introduction: To increase the carbon chain, substituting an alkyl group on alpha carbon of a carbonyl group is called alkylation.

Alkylation is carried out by reaction of a ketone with a secondary amine in the presence of an acid to form an enamine and then adding an appropriate alkyl halide. The alkylation is a ${\text{S}}_{\text{N}}\text{2}$ reaction. The alkylation works best with a primary alkyl halide.

Acylation is carried out by reaction of a ketone with a secondary amine in the presence of an acid to form an enamine and then adding an appropriate acyl halide. The acylation is an addition reaction.

(a)

Interpretation Introduction

Interpretation: It should be described that how the given compound is prepared from cyclohexanone using an enamine intermediate.

Concept introduction: To increase the carbon chain, substituting an alkyl group on alpha carbon of a carbonyl group is called alkylation.

Alkylation is carried out by reaction of a ketone with a secondary amine in the presence of an acid to form an enamine and then adding an appropriate alkyl halide. The alkylation is a ${\text{S}}_{\text{N}}\text{2}$ reaction. The alkylation works best with a primary alkyl halide.

Acylation is carried out by reaction of a ketone with a secondary amine in the presence of an acid to form an enamine and then adding an appropriate acyl halide. The acylation is an addition reaction.