Microbiology With Diseases By Taxonomy (6th Edition)
Microbiology With Diseases By Taxonomy (6th Edition)
6th Edition
ISBN: 9780134832302
Author: Robert W. Bauman Ph.D.
Publisher: PEARSON
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Chapter 18, Problem 9CT

A 43-year-old woman has been diagnosed with rheumatoid arthritis. Unable to find relief from her symptoms, she seeks treatment from a doctor in another country who injects antibodies and complement into her afflicted joints. Do you expect the treatment to improve her condition? Explain your reasoning.

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What is "defined as the structural differences (diversity) observed in the variable domains of antibodies?   This is for immunology.
Ms. House, a 32-year-old Hispanic woman, has had a history of intermittent pleuritic chest pain and joint pain for the past several years. Recently, she went to her physician because she noticed that an erythematous, butterfly-shaped rash had appeared on her face. Further lab tests indicated protein in her urine. Her blood test indicated the presence of numerous antinuclear antibodies, especially anti-DNA, and mature neutrophils containing nuclear material. A diagnosis of systemic lupus erythematosus (SLE) was made.   Discussion Questions Discuss how the presence of antibodies can cause such widespread damage in organ systems. (See SLE—Pathophysiology.) Discuss treatments for SLE and a prognosis for the patient in this case. (See SLE—Treatment.)
Ms. House, a 32-year-old Hispanic woman, has had a history of intermittent pleuritic chest pain and joint pain for the past several years. Recently, she went to her physician because she noticed that an erythematous, butterfly-shaped rash had appeared on her face. Further lab tests indicated protein in her urine. Her blood test indicated the presence of numerous antinuclear antibodies, especially anti-DNA, and mature neutrophils containing nuclear material. A diagnosis of systemic lupus erythematosus (SLE) was made.   Discussion Questions Discuss possible reasons why SLE was not diagnosed earlier. (See SLE—Clinical Signs and Symptoms.) Discuss how the presence of antibodies can cause such widespread damage in organ systems. (See SLE—Pathophysiology.) Discuss treatments for SLE and a prognosis for the patient in this case. (See SLE—Treatment.)
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