Principles of Human Physiology (6th Edition)
6th Edition
ISBN: 9780134169804
Author: Cindy L. Stanfield
Publisher: PEARSON
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Textbook Question
Chapter 18, Problem 29E
Explain the concept of transport maximum. Why does glucose appear in the urine of patients?
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Chapter 18 Solutions
Principles of Human Physiology (6th Edition)
Ch. 18.2 -
Describe the symptoms that indicate the presence...Ch. 18.2 - What treatments are available for removing or...Ch. 18.2 - Prob. 3CTQCh. 18.2 - Prob. 18.1.1QCCh. 18.2 - Prob. 18.1.2QCCh. 18.2 - Prob. 18.1.3QCCh. 18.2 - Prob. 18.1.4QCCh. 18.3 - Indicate whether the GFR will tend to rise or fall...Ch. 18.3 - Prob. 18.2.2QCCh. 18.3 -
Is the control of afferent and efferent...
Ch. 18.3 -
Describe the barriers for reabsorption and...Ch. 18.3 -
Describe the general mechanism of water...Ch. 18.3 -
Define the terms transport maximum and renal...Ch. 18.3 - Prob. 1CTQCh. 18.3 - Prob. 2CTQCh. 18.3 - Prob. 3CTQCh. 18.5 - Prob. 1CTQCh. 18.5 - Prob. 2CTQCh. 18.5 - Prob. 3CTQCh. 18.5 - Prob. 18.4.1QCCh. 18.5 - Prob. 18.4.2QCCh. 18.5 - Prob. 18.4.3QCCh. 18.5 -
Describe the innervation of the bladder,...Ch. 18 - Prob. 1ECh. 18 -
Which of the following is not one of the...Ch. 18 - Which type of specialized junction connects...Ch. 18 - Which of the following does not favor a large...Ch. 18 - Prob. 5ECh. 18 - Prob. 6ECh. 18 - Which of the following would occur if mean...Ch. 18 - Prob. 8ECh. 18 - Prob. 9ECh. 18 - Prob. 10ECh. 18 -
Micturition occurs in response to
a Relaxation...Ch. 18 - The (ureter/urethra) carries urine from the...Ch. 18 - Urinary excretion is the elimination of urine from...Ch. 18 -
The (afferent/efferent) arteriole carries blood...Ch. 18 - Prob. 15ECh. 18 - Prob. 16ECh. 18 - Prob. 17ECh. 18 - Prob. 18ECh. 18 - Prob. 19ECh. 18 - Prob. 20ECh. 18 - Prob. 21ECh. 18 - Prob. 22ECh. 18 -
Substances that are reabsorbed move into the...Ch. 18 - An increase in the flow rate through the macula...Ch. 18 -
Glucose reabsorption occurs primarily in the...Ch. 18 -
Describe the pathway of filtrate flow from the...Ch. 18 - Explain why the glomerular filtration rate does...Ch. 18 - Prob. 28ECh. 18 - Explain the concept of transport maximum. Why does...Ch. 18 - Prob. 30ECh. 18 - Prob. 31ECh. 18 - Prob. 32ECh. 18 - Prob. 33ECh. 18 -
Compare the responses of the smooth muscle in...
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- Active transport requires the use of ATP. Identify two ions that require active transport to be selectively reabsorbed.arrow_forwardExplain the mechanism how furosemide affects kidney tubules. How does this affect K+ balance? How different is the mechanism of thiazide affect urine production? Describe the process of acid-base regulation in human body.arrow_forwardGiven: A patient’s GFR (glomerular filtration rate) is 125 ml/min, and his urine is produced at a rate of 1.25 ml/min. (A) By what factor is the inulin concentrate in his urine. (B) The concentration of glucose in his plasma is 5 mmol/l. His renal reabsorption of glucose is completely inhibited. What would be the concentration of glucose in his urine? (answer parts a and b)arrow_forward
- Explain the reactions of the phosphate buffering system within the ICF.arrow_forwardIndicate whether the following sentences is True or False 1) Urea is the major nitrogen-containing metabolic product of protein catabolism in humans, accounting for > 75% of the nonprotein nitrogen eventually excreted 2) Dialysis is the process of separating substances in solution based on size and the difference in their diffusion rates through a semipermeable membranearrow_forwardSay someone has a blood glucose level of 245 mg/dl. Which statement below would be correct? O They would exhibit glycosuria because the transport maximum of glucose has been exceeded. O They would exhibit glycosuria because of decreased osmosis in the urine collecting duct. O They would not exhibit glycosuria because the transport maximum of glucose has been exceeded. O They would not exhibit glycosuria because of decreased osmosis in the urine collecting duct.arrow_forward
- Reabsorption involves what two methods of transport? Describe each. What determines which route a solute will take?arrow_forwardExplain how a high concentration of sodium ions in theinterstitial fluid affects intracellular fluid levels.arrow_forwardOne type of diuretic given to people with high blood pressure, renal disease and congestive heart failure are thiazide-type diuretics. These drugs inhibit sodium ion reabsorption by inhibiting the transport in the ascending limb of the loop of Henle. A) What does it mean to inhibit the transport of sodium ions in the loop of Henle? B) Explain how this inhibition of sodium ions in the loop of Henle could help increase urine production.arrow_forward
- Mention at least 5 proteins, besides albumin, that are present in the urine under pathological conditions. Explain why a glucose test that is normally reabsorbed in the proximal convoluted tubule may appear in the urine, and state the renal threshold levels for glucose.arrow_forwardDefine sodium–glucose transporter (SGLT)arrow_forwardThe Na+-glucose transporters SGLT2 and SGLT1 are located at different levels of the kidney proximal tubule to minimize spillover of the glucose into the urine (See diagram attached) a) Consider the Na+-glucose coupling ratios for SGLT2 and SGLT1. Why would localization of SGLT2 in the early proximal tubule and SGLT1 in the late proximal tubule be advantageous? b) The Michaelis constant (Km) for the SGLT2 and SGLT1 transporters are 2 mM and 0.5 mM, respectively. Is SGLT2 or SGLT1 the higher affinity Na+-glucose transporter? d) Dapagliflozin is an SGLT1 inhibitor and commonly prescribed to treat type 2 diabetes. Why would this be of benefit to a diabetes patient?arrow_forward
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