Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 18, Problem 15QP
Summary Introduction
To determine: The genetic nature of a bipolar disorder.
Introduction: A bipolar disorder (manic-depressive disorder) is a type of mental illness which affects a number of human beings per year. This condition occurs during the adolescence or in the second and third decades of life.
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The Xb locus on Alouatta genus, the howler monkey X chromosome has 2 alleles, b+ and b. The
b+ allele causes the presence of the Xb surface protein on their granulocyte cells, while the
recessive allele b which does not allow the antigen to appear. The Xb locus is at 15
centimorgans, from the GRG locus. The GRG locus produces a normal enzyme activity.
Individual howler monkeys with one form of an eye condition have the grg/grg genotype, with
the males grg/Y presenting the condition. A male howler monkey with the eye condition caused
by this enzyme mutation and no Xb antigen has a normal female howler monkey daughter with
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mating from a male howler monkey from a different tree.
A) Determine the genotype of the howler monkey daughter, from the problem.
B) Determine the types and percentages of each gametes in oogenesis produced of the
howler monkey daughter female, based on the map distance given.…
Match each example of mutation to the correct effect on function.
Hypomorphic
mutation
Hypermorphic
mutation
Antimorphic
mutation
Neomorphic
A deletion results in the loss of part of a protein and the protein
retains some of its normal activity.
A mutant allele makes a protein with increased cataytic activity.
A mutant form of a transcription factor binds new DNA sequences to
activate different genes.
A mutant from of a receptor protein interferes with the function of
the wild-type receptor through heterodimerization.
Angelica just learned that her paternal uncle, Aaron, passed away from hypertrophic cardiomyopathy (autosomal dominant). Angelica’s father was killed in a duty as a young man, and therefore, his status is unknown. Her two sisters, Eliza and Peggy, have been tested for the known causative mutation in the family and do not have it. What is the chance that Angelica has the familial mutation for HCM?
Group of answer choices
1/33
1/10
1/21
Chapter 18 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 18.2 - What role would twin and adoption studies play in...Ch. 18.2 - Prob. 2EGCh. 18 - Why do you think it has been so difficult to...Ch. 18 - If a test were available that could tell you...Ch. 18 - Prob. 1QPCh. 18 - Prob. 2QPCh. 18 - Prob. 3QPCh. 18 - List the steps involved in transmitting a nerve...Ch. 18 - Why do neurotransmitters have to be removed from...Ch. 18 - Prob. 6QP
Ch. 18 - Perfect pitch is the ability to identify a note...Ch. 18 - Prob. 8QPCh. 18 - Name three genes whose mutations lead to an...Ch. 18 - Prob. 10QPCh. 18 - Prob. 11QPCh. 18 - Animal Models: The Search for Behavior Genes You...Ch. 18 - Prob. 13QPCh. 18 - A pedigree analysis was performed on the family of...Ch. 18 - Prob. 15QPCh. 18 - A region on chromosome 6 has been linked to...Ch. 18 - Genetics and Social Behavior Of the following...Ch. 18 - Prob. 18QPCh. 18 - Prob. 19QP
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