Anatomy and Physiology by OpenStax
17th Edition
ISBN: 9781506698021
Author: J. Gordon Betts;Dean H. Kruse;Kelly A. Young;Peter DeSaix;Brandon Poe;Oksana Korol;James A. Wise;Eddie Johnson;Jody E. Johnson;Mark Womble
Publisher: XANEDU PUBLISHING
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Textbook Question
Chapter 17, Problem 9RQ
A small molecule binds to a G protein, preventing its activation. What direct effect will this have on signaling that involves cAMP?
- The hormone will not be able to bind to the hormone receptor.
- Adenylyl cyclase will not be activated.
- Excessive quantities of cAMP will be produced.
- The phosphorylation cascade will be initiated.
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Chapter 17 Solutions
Anatomy and Physiology by OpenStax
Ch. 17 - Visit this link...Ch. 17 - Visit this link...Ch. 17 - Visit this link...Ch. 17 - Visit this link...Ch. 17 - Visit this link...Ch. 17 - Endocrine glands ________. secrete hormones that...Ch. 17 - Chemical signaling that affects neighboring cells...Ch. 17 - A newly developed pesticide has been observed to...Ch. 17 - A small molecule binds to a G protein, preventing...Ch. 17 - A student is in a car accident, and although not...
Ch. 17 - The hypothalamus is functionally and anatomically...Ch. 17 - Which of the following is an anterior pituitary...Ch. 17 - How many hormones are produced by the posterior...Ch. 17 - Which of the following hormones contributes to the...Ch. 17 - Which of the following statements about the...Ch. 17 - The secretion of thyroid hormones is controlled by...Ch. 17 - The development of a goiter indicates that...Ch. 17 - Iodide ions cross from the bloodstream into...Ch. 17 - When blood calcium levels are low, PTH stimulates...Ch. 17 - Which of the following can result from...Ch. 17 - The adrenal glands are attached superiorly to...Ch. 17 - What secretory cell type is found in the adrenal...Ch. 17 - Cushings disease is a disorder caused by ________....Ch. 17 - Which of the following responses s not part of the...Ch. 17 - What cells secrete melatonin? melanocytes...Ch. 17 - The production of melatonin is inhibited by...Ch. 17 - The gonads produce what class of hormones? amine...Ch. 17 - The production of FSH by the anterior pituitary is...Ch. 17 - The function of the placental hormone human...Ch. 17 - If an autoimmune disorder targets the alpha cells,...Ch. 17 - Which of the following statements about insulin is...Ch. 17 - The walls of the atria produce which hoimone?...Ch. 17 - The end result of the RAAS is to ________. reduce...Ch. 17 - Athletes may take synthetic EPO to boost their...Ch. 17 - Hormones produced by the thymus play a role in the...Ch. 17 - The anterior pituitary gland develops from which...Ch. 17 - In the elderly, decreased thyroid function causes...Ch. 17 - Describe several main differences in the...Ch. 17 - Compare and contrast endocrine and exocrine...Ch. 17 - True or false: Neurotransmitters are a special...Ch. 17 - Compare and contrast the signaling events involved...Ch. 17 - Describe the mechanism of hormone response...Ch. 17 - Compare and contrast the anatomical relationship...Ch. 17 - Name the target tissues for prolactin.Ch. 17 - Explain why maternal iodine deficiency might lead...Ch. 17 - Define hyperthyroidism and explain why one of its...Ch. 17 - Describe the role of negative feedback in the...Ch. 17 - Explain why someone with a parathyroid gland tumor...Ch. 17 - What are the three regions of the adrenal cortex...Ch. 17 - If innervation to the adrenal medulla were...Ch. 17 - Compare and contrast the short-term and long-term...Ch. 17 - Seasonal affective disorder (SAD) is a mood...Ch. 17 - Retinitis pigmentosa (RP) is a disease that causes...Ch. 17 - Compare and contrast the role of estrogens and...Ch. 17 - Describe the role of placental secretion of...Ch. 17 - What would be the physiological consequence of a...Ch. 17 - Why is foot care extremely important for people...Ch. 17 - Summarize the role of GI tract hormones following...Ch. 17 - Compare and contrast the thymus gland in infancy...Ch. 17 - Distinguish between the effects of menopause and...
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- A hormone molecule binds to a receptor on a cell membrane. It doesnt enter the cell; rather, the binding activates a second messenger inside the cell that triggers an amplified response to the hormonal signal. Is the signaling molecule a steroid or a nonsteroid hormone?arrow_forwardOverexpression of this receptor in the cells of the adrenal gland causes Cushing's syndrome, a disease caused by the overproduction of cortisol. One strategy that scientists have employed to treat this disease is the use of small molecules that bind to, but do not activate, MC2R. This type of molecule is generically referred to as an antagonist. How can an antagonist bind to the same receptor as ACTH but not activate it? O a. The antagonist can bind covalently while ACTH binds non-covalently O b. The antagonist is only partially complimentary to the binding pocket of MC2R O The antagonist binds to ACTH and blocks it from binding to the receptor properly O d. The antagonist is the exact same structure as ACTH but since it is synthetic it doesn't work One cause of Cushing's syndrome is the inappropriate production of GPCRS in the adrenal gland that are not normally present in those cells. When these receptors are activated they result in the production of cortisol. Which statement about…arrow_forwardPlace the following steps (showing how a steroid hormone changes the activities of its target cells) in order of what happens first, second, third, fourth, and last. Refer to image. The hormone-receptor complex enters the nucleus of the cell and binds to the DNA. The steroid hormone passes through the cell membrane. The hormone attaches to a receptor in the cytoplasm, forming a hormone-receptor complex. A gene in the DNA is activated, and transcription and translation take place. Proteins that alter the cell′s activities, such as enzymes, are made. 2. Place the following steps (showing how a hydrophilic hormone changes the activities of its target cells) in order of what happens first, second, third, and last. Refer to image. The activity of the target cell is changed by the final enzyme in the cascade. The second messenger activates or deactivates certain enzymes in a cascade fashion. A second messenger is activated. Hormone binds to a receptor protein.arrow_forward
- What is the difference between a G protein and a receptor tyrosine kinase? Give an example of a hormone that uses each.arrow_forwardWhich statement correctly identifies how a lipid-soluble hormone that diffuses from the blood and through the interstitial fluid identifies which cells in the tissue to act upon? O The cell closest to the diffusion site. O The presence of a receptor located in the cytoplasm or nucleus specific to the hormone in cells. O The presence of a receptor embedded in the plasma membrane of target cells. O The presence of a channel protein embedded in the plasma membrane for the lipid-soluble hormone to diffuse through. Save for Later 80 F3 F4 F5 F6 8 F7 Attempts: 0 of 3 used F8 F9 Submit Answer F10arrow_forwardWhich of the following steps amplify the epinephrine signal response in cells: receptor activation of G protein, G protein activation of adenylyl cyclase, cAMP activation of PKA, or PKA phosphorylation of glycogen phosphorylase kinase (GPK)? Which change will have a greater effect on signal amplification: an increase in the number of epinephrine receptors or an increase in the number of Gαs proteins?arrow_forward
- Glycogen breakdown is stimulated by a signaling cascade that is an excellent example of signal amplification. Amplification in glycogen breakdown is where a small number of signal molecules (hormones) activate a rapid and large release of glucose. Which of the following is the correct sequence for this signaling cascade in skeletal muscle cells? O epinephrine, GPCR, Protein kinase A (PKA), phosphorylase b kinase O insulin, insulin receptor (RTK), protein phosphatase-1 (PP1), glycogen phosphorylase glucagon, GPCR, Protein kinase A (PKA), glycogen synthase O epinephrine, protein phosphatase-1 (PP1), phosphorylase b kinase, glycogen synthase insulin, insulin receptor (RTK), protein phosphatase-1 (PP1), bifunctional enzyme, glycogen synthasearrow_forwardWhich of the following is NOT part of a liver cell's response to epinephrine? Phosphorylation of phosphorylase kinase activation of Protein kinase A GDP phosphorylation by G-alpha production of cAMParrow_forwardWhat kind of protein is the reactor in insulin signaling pathway: a ligand-gated channel, a G protein-linked receptor, or an enzyme- linked receptor? The receptor activates a specific kind of protein, Based on what that protein does, what is it called?arrow_forward
- Under in vivo conditions, chronic treatment with a noncompetitive antagonist may lead to the up-regulation of the targeted receptor over time. True False Cytokines are peptides that are generally made in advance by specific types of cells, stored in vesicles, and act as autocrine or paracrine factors. True False Thyroid hormone is stored in an extracellular compartment. True Falsearrow_forwardThis is a signaling pathway that involves a second messenger: epinephrine → G protein-coupled receptor → G protein → adenylyl cyclase → cAMP. Which one is known as the second messenger?arrow_forwardCompare and contrast signaling events in the nervous vs. endocrine systems. How does a “message” get from the original neuron or endocrine gland to the target? How does the signal get transduced into something the target cell can respond to? Be sure to include a description of the signaling molecules and cellular receptors involved in each of these systems.arrow_forward
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