To review:
The outcome of a toxin that results in creating the same length of the refractory period in cardiac muscles as present in the skeletal muscles.
Introduction:
The heart muscles generate an action potential due to the depolarization of the sinoatrial node (SA node) of the heart, which acts as a natural pacemaker. The action potential leads to muscular contraction, which helps the heart to supply blood to the whole body. The other cells that have the capability to generate an action potential as a result of the depolarization are the skeletal muscle cells and the neuron cells. After one action potential is generated, the cell becomes resistant to generating another action potential for a few seconds. This period is termed as the refractory period.
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Human Anatomy & Physiology (2nd Edition)
- Fill in the following blanks (a - f) regarding the Baroreceptor Reflex Control: The baroreceptor reflex control is a negative feedback loop. If the patient is hypotensive, they are experiencing a decrease in blood pressure detected by (a.)_ located in the aortic and carotid bodies. The afferent pathways include the (b.)_ nerve and the (c.)__ nerve. These synapse at the cardioregulatory and vasomotor integration centers located in the (d.)_ These centers will cause the heart rate to (e.)(increase/decrease) and blood vessels to (f.) (vasodilate/vasocontrict). For the toolbar press ALT+510 (BC) or ALTHEN±+510/Madarrow_forwardThe plasma membranes of adjacent cardiac muscle cells are connected via ____________, in which ____________ tie the cells together and ____________allow current (ions) to flow from one cell to the next (electrical coupling).arrow_forwardWhen you exercise, your heart speeds up, and a greater volume of blood is pumped around the body to meet demands. Both heart rate and stroke volume are affected by changes in blood gases, blood pressure, temperature and movement. Make reference to the following to help structure your answer: Inputs: Chemoreceptors Stretch receptors Thermoreceptors Pressure receptors How the information is processed by the brain Effectors – what nerves regulate heart rate in response to changes in each direction. Explain this concept in no more than 300 words. You must make reference to the nervous system in the control of these events.arrow_forward
- Caffeine lowers the heart rate by increasing rates of depolarization at the SA node True False Nicotine raises the heart rate because it stimulates the activity of the sympathetic neurons in medulla oblongata True False The Frank-Starling Law of the Heart states that the force of heart contraction is directly proportional to the initial length of the muscle fiber, within optimal limits of length True False If the sarcomeres stretched beyond the optimal length, the force of contraction would go down, but that can potentially happen only during open heart surgery when the heart is not constrained by the pericardium, lungs, ribs and diaphragm. True False It is the Na+ channel-driven spontaneous depolarization that is affected by sympathetic and parasympathetic inputs to speed up or slow down the firing rate of the SA node and other conductive cells. True Falsearrow_forwardWhich of the following characteristics imparts autorhythmic cells with the ability to function myogenically? a the have prolonged action potentials due to the action of Ca2+ which causes a plateau during depolarization b they have a threshold that is below their resting membrane potential c their action potentials are controlled by mechanically-gated ion channels instead of voltage-gated channels d they have If channels which increase permeability to Na+ at rest, causing depolarization to threshold e the rising, depolarization, phase of their action potential is due to Ca2+ influx instead of Na+ influx.arrow_forwardWhy do the cardiac muscles cells demonstrateautorhythmicity?arrow_forward
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- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning