Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 16, Problem 9QP
Cystic fibrosis is an autosomal disease that mainly affects the white population, and 1 in 20 whites are heterozygotes. Genetic testing can diagnose heterozygotes. Should a genetic screening program for cystic fibrosis be instituted? Should the federal government fund it? Should the program be voluntary or mandatory, and why?
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Huntington's disease is an inherited autosomal dominant disorder that can affect both men and women. Imagine a couple has had
seven children, and later in life, the husband develops Huntington's disease. He is tested and it is discovered he is heterozygous
for the disease allele, Hh. The wife is also genetically tested for the Huntington's disease allele, and her test results show she is
unaffected, hh.
What is the percent probability that the first child of this couple will have Huntington's disease?
probability:
%
What is the percent probability that two of the seven children will have Huntington's disease?
probability:
%
Below is a pedigree chart for a family that has a history of Alkaptonuria. Individuals infected with this condition can have darkened skin, brown urine, and can suffer from joint damage and other complications. Given this pedigree answer the following questions.
Given the data in the pedigree chart is this genetic condition autosomal dominant or autosomal recessive?
What are the genotypes for #1, #2, and #3?
If either of the 4th generation "aa" females were to mate with a homozygous dominant male would any of their offspring illustrate the phenotype? Why or why not?
Cystic fibrosis (CF) is an autosomal recessive trait. A three-generation pedigree is shown below for a family that carries the mutant allele for cystic fibrosis. Note that carriers are not colored in to allow you to figure out their genotypes. Normal allele = F CF mutant allele = f
What is the genotype of individual #13?
A) ff
B) FF
C) Ff
D) it is impossible to tell
Chapter 16 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 16.5 - Should fertility clinics be required to disclose...Ch. 16.5 - Prob. 2EGCh. 16 - Would ISCI be an option? Why or why not? Jan, a...Ch. 16 - Jan is concerned about using ART. She wants to be...Ch. 16 - List the common infertility problems in women....Ch. 16 - Prob. 2QPCh. 16 - Prob. 3QPCh. 16 - What is the difference between gamete...Ch. 16 - Why should women consider collecting and freezing...Ch. 16 - Prob. 6QP
Ch. 16 - Researchers are learning how to transfer...Ch. 16 - Prob. 8QPCh. 16 - Cystic fibrosis is an autosomal disease that...Ch. 16 - Prob. 10QPCh. 16 - Gene therapy involves: a. the introduction of...Ch. 16 - In selecting target cells to receive a transferred...Ch. 16 - The prospect of using gene therapy to alleviate...Ch. 16 - Is gene transfer a form of eugenics? Is it...Ch. 16 - A couple who wishes to have children visits you, a...Ch. 16 - A couple has had a child born with...Ch. 16 - You are a genetic counselor, and your patient has...Ch. 16 - Prob. 18QP
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- Albinism is an autosomal (not sex-linked) recessive trait. A man and woman are both of normal pigmentation and have one child out of three who is albino (without melanin pigmentation). What are the genotypes of the albino's parents? One parent must be homozygous for the recessive allele; the other parent can be homozygous dominant, homozygous recessive, or heterozygous. Both parents must be homozygous dominant. One parent must be heterozygous; the other parent can be homozygous dominant, homozygous recessive, or heterozygous. Both parents must be heterozygous. One parent must be homozygous dominant; the other parent must be heterozygous. O000arrow_forwardCystic fibrosis in humans is caused by a recessive allele. A man is known to be a carrier of the cystic fibrosis allele. He marries a phenotypically normal woman. In the general population, the incidence of cystic fibrosis at birth is approximately 1 in 1,700. Assume Hardy-Weinberg proportions. What is the probability that the wife is also a carrier? Answer in decimal number only (three decimal places; example: 0.123). What is the probability that their first child will be affected? Answer in decimal number only (three decimal places; example: 0.123).arrow_forwardDuchenne muscular dystrophy is sex linked and usually affects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brother has Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’s disease, what is the probability that you have received the allele?c. If your father’s brother had the disease, what is the probability that you have received the allele?arrow_forward
- The allele for albinism is recessive to the allele for normal skin pigmentation. All individuals who are homozygous for this recessive allele (m) are unable to produce the enzyme needed for melanin production and are referred to as albinos. In the following statements, determine the correct genotypes: An albino male (genotype A) whose parents both have normal skin pigmentation (genotype B) marries a woman who does not have albinism (genotype C). This woman’s father is an albino (genotype D). The married couple has three children, two with normal skin pigmentation (genotype E) and one exhibiting albinism (genotype F)arrow_forwardEpilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations and sometimes loss of awareness. For epilepsy, the concordance values are 72% for monozygotic twins and 15% for dizygotic twins. 1) Is this a single gene inheritance or multifactorial disease? 2) Is there a strong genetic or environmental cause to the development of this disease? If both genetic and environmental causes are implicated, you have to indicate each of them separately.arrow_forwardAlbinism is a recessive disorder where there is a lack of melanin. Andrea and her husband Claude both have normal skin pigmentation. Andrea’s mother has the albino phenotype, but her father and her brother do not (normal pigmentation). Claude’s parents are both normal, but he has a sister who has the condition (is albino). Answer the following questions If Andrea and Claude are carriers for the albino allele, what is the probability that they have an albino child? If Andrea and Claude have a second child, what is the probability this child be normal (non-albino)? NOTE: Draw a punnet square or show your work.arrow_forward
- In a paternity suit, a woman with type O blood claims that a man with type AB blood is the father of her type O baby. List the genetypes of the mom, man, and baby. Can the woman prove he is the father or can he is not? Why or why not? If the accused man was type A insyead of type AB, what would be his possible genotypes? Could the woman prove he is the father? Can the man prove he is not the father? Why or why not?arrow_forwardAlbinism is an autosomal (not sex-linked) recessive trait. A man and woman are both of normal pigmentation and have one child out of three who is albino (without melanin pigmentation). What are the genotypes of the albino's parents? Both parents must be homozygous dominant. Both parents must be heterozygous. One parent must be homozygous dominant; the other parent must be heterozygous. One parent must be heterozygous; the other parent can be homozygous dominant, homozygous recessive, or heterozygous. One parent must be homozygous for the recessive allele; the other parent can be homozygous dominant, homozygous recessive, or heterozygous. O O O O Oarrow_forwardHuntington's Chorea is an autosomal dominant trait. Below is a pedigree of a family with Huntington's disease. If III-6 had a child with a healthy individual, what would be the chance they would have a child with Huntington's? Group of answer choices a 100% b 25% c 50% d 0%arrow_forward
- Hemophilia is an X-linked disorder that affects the body’s ability to create blood clots. The allele for normal blood clotting, XH, is dominant over the allele for hemophilia, Xh. An unaffected female that is not a carrier mated with an affected male. Which of the following rows identifies the possible genotypes of the offspring? Select one: a. Female Male XHXH and XHXh XHY and XhY b. Female Male XHXh XHY c. Female Male XHXh XHY and XhY d. Female Male XHXH and XHXh XHYarrow_forwardCystic fibrosis is a disease that is passed down through the generations. The recessive alleles for cystic fibrosis are heterozygous carriers in both parents. What is the probability that one of their children may develop cystic fibrosis?arrow_forwardAlbinism is an autosomal recessive condition characterized by absence of melanin pigment from the skin, eye and hair. Two carriers of albinism marry and plan to have FIVE children. Assume a 1:1 sex ratio. What is the probability that at least 3 children will be normal?arrow_forward
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