Concept explainers
a.
To determine: The possible method to handle the scenario in which an individual should contact the proband beforehand to explain the results and the implications of the results.
Introduction: A couple has undergone a prenatal test in which the young woman (proband) is found to have the sickle cell trait (Ss), and her partner does not have the sickle cell anemia (SS). The woman’s family has a family history of sickle cell anemia. Their prenatal tests indicate that the fetus is affected with sickle cell anemia (ss) and the only way it is possible is when the woman’s partner is not the father of the fetus.
b.
To determine: Whether it is appropriate to keep the information from the partner as he believes he is the father of the baby and the other problems related to this case.
Introduction: A couple has undergone a prenatal test in which the young woman (proband) is found to have the sickle cell trait (Ss), and her partner does not have the sickle cell anemia (SS). The woman’s family has a family history of sickle cell anemia. Their prenatal tests indicate that the fetus is affected with sickle cell anemia (ss) and the only way it is possible is when the woman’s partner is not the father of the fetus.
Trending nowThis is a popular solution!
Chapter 16 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
- As a genetic counselor, you inform Susan and John that a blood test for cystic fibrosis is available. would you recommend generic testing for Susan and John?arrow_forwardO. 2 Hemophilia A is an X-linked trait where blood clotting is affected due to a mutation in a clotting factor protein. Georgio has hemophilia and attends a support group where he meets Gbenga, who does not have the disease, but whose father has hemophilia. Her mother is not affected. A) If they marry, what percentage % of all their children will have hemophilia? % B) Georgio meets another woman, Maria, at the hemophilia support group. Maria also lacks the trait, but her mother has hemophilia while her father is unaffected. # 3 Would a Georgio-Maria mating provide a larger chance of having afflicted children compared to a Georgio-Gbenga mating? C) Show how you came up with your answer to B. Edit View Insert Format Tools Table 12pt ✓ 80 F3 V Paragraph ✓ $ 4 Yes or No 000 000 F4 DO LO % 5 BIUAV T² | F5 ^ MacBook Air 6 2 F6 V & 7 F7 * 8 DII F8 ( 9 DD F9 1 0 S Farrow_forwardA young lady requested pre-marital genetic counselling because her sister had died in infancy of gangliosidosis, an autosomal recessive disease. What is the risk that this young lady has similarly affected offspring? What advice should be given?arrow_forward
- As a genetic counselor, you inform Susan and John that a blood test for cystic fibrosis is available. Would you recommend genetic testing for Susan and John? Explain.arrow_forwardA genetic counsellor is working with a couple who have just had a child who has a debilitating autosomal recessive form of a disease termed epidemolysis bullosa (which causes severe external and internal skin fragility resulting in blistering etc). Neither parent has epidemolysis bullosa, nor does anyone in their families. What should the counsellor say to this couple? OA. "Because no one in either of your families has epidemolysis bullosa, you are not likely to have another baby with epidemolysis bullosa. You can safely have another child." OB. "Because you have had one child with epidemolysis bullosa, you must each carry the allele. Any child you have has a 50% chance of having the disease." OC. "Because you have had one child with epidemolysis bullosa, you must each carry the allele. Any child you have has a 25% chance of having the disease." OD. "Because you have had one child with epidemolysis bullosa, you must both carry the allele. However, since the chance of having an affected…arrow_forwardThere are six types of agglutinogen named C,D, E and c,d,e.the first three are dominant and last three are recessive.discussarrow_forward
- Tuberous Sclerosis (TS) is an autosomal dominant genetic disease characterized by seizures, mental retardation, autism, and benign tumors of the brain, heart, skin, and kidneys. The kidney tumors can also be malignant. This disease exhibits a wide range of severity, and only about 1/3 of the cases are inherited. Two different genes have been tightly linked to the disease in families where it is inherited. The remaining 2/3 appear to be due to mutations in one of the 2 genes as well. Overall it appears that 1/2 are caused by mutations in TSC1 and the other half by mutations in TSC2. A rat model for hereditary renal carcinoma (kidney cancer) has been found. Southern and Northern blot analysis of the TSC1 and TSC2 gene revealed no differences between these rats and normal rats. Not all the rats in the strain would get cancer but a significant proportion did and those were selected for and used in experiments. 1. a) What was detected by the Southern blots? (look this up, make your…arrow_forwardCystic Fibrosis (CF) is an autosomal recessive condition. Therefore, heterozygous (Cc) carriers do not display symptoms. Two parents who are carriers plan to start a family and you are a genetic counselor helping to advise them about their chances of having children affected by CF. a) Suppose the couple has 4 children, each one year apart. What is the probability that all 4 children will inherit CF? b) What is the probability that any 3 of their 4 children will not inherit CF, but 1 will be affected? c) What is the probability that their first child will not inherit CF, but the younger 3 children will inherit CF?arrow_forwardHello, i understand the question, but i only need to know which option is right, no need for explanation. I mean jsut say which option, thanks in advance.arrow_forward
- A 20-year-old woman comes to your genetic counselling center because she knows that Huntington disease occurs in members of her family. Huntington is an autosomal dominant disease that often becomes apparent around 35–40 years of age. Her paternal grandfather was afflicted, but so far her 41 year old father shows no symptoms. Her two great-great grandmothers on her father's side were healthy well into their 90s, and one of her great-great grandfathers died of unknown causes at 45. Testing for Huntington disease is extremely expensive, but she is concerned that she may fall victim to this disease and wants to plan her life accordingly. After examining her pedigree you advise her to: not get tested because her father is only a carrier and it is very unlikely her mother is a carrier. not get tested because there is no possibility that she is homozygous. get tested because her father could be a carrier. not get tested because only males in her family get the disease. not get tested…arrow_forwardAthena Williams was born as a healthy baby girl- and while she was small (25th percentile) the family pediatrician wasn’t worried as both her parents were petite. However at about the age of 13 months Athena stopped running around, tired easily, was pale and lost her appetite- symptoms that could not be explained by a recent flu bug going around as it lasted for months. Concerned the family pediatrician Dr. Wright decided to draw Athena’s blood to check for inherited blood-disorders. At the next office visit, Dr. Wright sat Athena’s mother down and gently gave her the bad news. As suspected it was determined that Athena had Thalassemia- an inherited disorder resulting from a defective for β-globin protein- and thus defective Hemoglobin [Like sickle cell anemia]. β-thalassemia patients are treated with frequent transfusions requiring many hospital visits, but this is not a cure. Individuals with severe forms of β-thalassemia often die in mid-teens. Dr. Wright suggested to Athena’s…arrow_forwardAthena Williams was born as a healthy baby girl- and while she was small (25th percentile) the family pediatrician wasn’t worried as both her parents were petite. However at about the age of 13 months Athena stopped running around, tired easily, was pale and lost her appetite- symptoms that could not be explained by a recent flu bug going around as it lasted for months. Concerned the family pediatrician Dr. Wright decided to draw Athena’s blood to check for inherited blood-disorders. At the next office visit, Dr. Wright sat Athena’s mother down and gently gave her the bad news. As suspected it was determined that Athena had Thalassemia- an inherited disorder resulting from a defective for β-globin protein- and thus defective Hemoglobin [Like sickle cell anemia]. β-thalassemia patients are treated with frequent transfusions requiring many hospital visits, but this is not a cure. Individuals with severe forms of β-thalassemia often die in mid-teens. Dr. Wright suggested to Athena’s…arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning