Concept explainers
Case Summary:
A drug is known to decrease heart rate even after cutting T1-T4 white rami. After cutting the vagus nerve, the drug no longer affects the heart rate. It affects the preganglionic and postganglionic neurons. The effect of the drugs is either inhibitory or excitatory.
Adequate Information:
The Autonomic Nervous System (ANS) controls the unconscious movement of the body. It has two important divisions’ sympathetic and parasympathetic divisions. They are present on the preganglionic neuron of the CNS and autonomic ganglia of the PNS. The sympathetic axons travel through the sympathetic chain ganglia to their target cell. The parasympathetic axons travel from cranial and sacral nerves to the target tissue. These branches of nerves either supply the organ or join nerve plexus.
To determine:
The drugs affect the ANS division. The effect caused by the drugs on the synapse between preganglionic and postganglionic neurons. The drug effect is inhibitory or exhibitory.
Given Information:
The parasympathetic division of the brainstem of medulla oblongata controls the effect of the drugs and get excited. By cutting the vagus nerve the effect of the drug get eliminated because it is no longer acting between the preganglionic and postganglionic synapses
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SEELEY'S ANATOMY+PHYSIOLOGY
- The ANS is subdivided into sympathetic and parasympathetic divisions. Review the differences between these two divisions by filling in the table below: Characteristic Sympathetic or Parasympathetic? Calms you down — "rest and digest" ["", ""] Pumps you up — "fight or flight" ["", ""] Preganglionic neuron long, postganglionic neuron short ["", ""] Preganglionic neuron short, postganglionic neuron long ["", ""] Arises from cranial or sacral spinal nerves ["", ""] Arises from spinal nerves T1-L2 ["", ""] Synapses near the spinal cord ["", ""] Synapses near the target organ ["", ""] Increases heart and respiratory rate ["", ""] Stimulates…arrow_forwardIn the sympathetic division of the autonomic nervous system: Select one: The ratio between the number of postganglionic and preganglionic neurons is small. A single preganglionic neuron usually synapses with a single postganglionic neuron. An important functional characteristic is convergence of the preganglionic fibers. Preganglionic fibers are usually much longer than the postganglionic fibers. Activity of the neurons tends to have a more generalized and widespread effect on the body.arrow_forwardWhich of the following is not correct about the parasympathetic division? Select one: O A. parasympathetic nerves constitute a part of the autonomic nervous system O B. the neurotransmitter released by preganglionic neurons is acetylcholine O C. parasympathetic nerves always form synapses in ganglia near or within an internal organ O D. the neurotransmitter released by postganglionic neurons is acetylcholine O E. parasympathetic nerves exit the central nervous system at the thoracic and lumbar regions of the spinal cordarrow_forward
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- Compare the primary mechanisms used by the sympathetic and parasympathetic divisions to clear or remove neurotransmitters? In other words, how do they terminate their neurotransmitter activity? How do they differ from each other? Question #2 Barbra Streisand, age 79, has asthma. We are considering an adrenergic drug for treatment. For Ms. Streisand, what are the drug advantages and diadvantages associciated with the use of ephedrine isoproterenol metaproterenol albuterol terbutaline Would her age be a factor in selecting the best drug? Explain. Question #3 Steven Seagal, age 69, has hypertension and asthma. We are considering treating him with an adrenergic blocker. What are the advantages and disadvantages for each of the drugs below to treat high blood pressure? doxazosin prazosin propranolol metoprolol atenolol acebutolol What needs to be included when teaching individuals suffering from high blood pressure about the use of an adrenergic blocker?arrow_forwardSympathetic ganglia are proximal to the effector organs and glands O are located distal to the spinal cord O are in the sacral region are located proximal to the spinal cordarrow_forwardWhere are the cell bodies of sympathetic preganglionicneurons located?arrow_forward
- Which ANS fibers release acetylcholine? Which release norepinephrine?arrow_forwardWhich of the following is a feature exclusively of the sympathetic division of the ANS? Select one: O a. Postganglionic axons tend to be localized to a single effector O b. Most preganglionic axons are short O. None of these options is a feature of the sympathetic system O d. Preganglionic neurons extend from the brain stem or sacral elements of the spinal cordarrow_forwardThere are two divisions of the autonomic nervous system: Sympathetic and parasympathetic Describe 5 effects of parasympathetic activation. How does this help the body return to normal activities after exertion?arrow_forward
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