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Concept explainers
To explain: The reason why two steps of pyruvate oxidative decarboxylation, do not involves any of the three carbons of pyruvate, but are necessary for the operation of PDH complex.
Introduction: Pyruvate is obtained from glycolysis and then transported into matrix of mitochondria through mitochondrial pyruvate carrier. In mitochondrial matrix, an enzyme called pyruvate dehydrogenase complex (PDH) converts the pyruvate into acetyl-CoA.
Three types of enzyme are involved in the composition of PDH. These enzymes are
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Chapter 16 Solutions
Loose-leaf Version for Lehninger Principles of Biochemistry 7E & SaplingPlus for Lehninger Principles of Biochemistry 7E (Six-Month Access)
- BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. FreemanLehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. FreemanFundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
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