EBK SEELEY'S ANATOMY & PHYSIOLOGY
11th Edition
ISBN: 9781259671166
Author: VanPutte
Publisher: MCGRAW HILL BOOK COMPANY
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Chapter 15, Problem 10RAC
Summary Introduction
Introduction:
The rods in the retina are the bipolar photoreceptor that is involved in non-color vision. They are involved in vision under reduced light conditions. Rod contains rhodopsin that has the photosensitive pigment known as retinal covalently bound to opsin protein.
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Given these events:(1) Bipolar cells depolarize.(2) Glutamate release from presynaptic terminals of photoreceptorcells decreases.(3) Light strikes photoreceptor cells.(4) Photoreceptor cells are depolarized.(5) Photoreceptor cells are hyperpolarized.Choose the arrangement that lists the correct order of events, startingwith the photoreceptor cells in the resting, nonactivated state.a. 1,2,3,4,5 b. 2,4,3,5,1 c. 3,4,2,5,1 d. 4,3,5,2,1 e. 5,3,4,1,2
Based on the attached figure (Figure 9.8 in the textbook), what is
the actual membrane mechanism mediating the light-induced
hyperpolarization of a photoreceptor?
(A) Dark
Rod outer segment
CGMP
0
CGMP
CGMP
CGMP
K+
Rod inner
segment
Inside
Obelecendra
EX
Ca²+
Na+
Outside
Na+ influx,
K+ efflux:
Depolarization
(B) Light
Rod outer segment
LIELITI
CGMP
reduced
Rod inner
segment
Ca2+
Na
Inside
Outside
Reduced Na+ influx,
K* efflux:
Hyperpolarization
Retinal is therefore a key player that triggers a series of activation in phototransduction (see figure
below).
Phototransduction in photoreceptor cells
Disc membrane
1000000000………………………….
Disc lumen
Light
Rhodopsin
GDP
Transducin
Photoreceptor cytosol
GTP
GTP
GTP
PDE
CGMP
CGMP
inhibition
CGMP
GMP
PDE6i
GMP
GMP
Extracellular
environment
Plasma
membrane
1. Light hits the retinal molecule and changes into an all-trans configuration
2. This change in the retinal conformation activates the rhodopsin photoreceptor
3. The rhodopsin photoreceptor then activates a specific heterotrimeric G protein called
transducin.
4. The transducin then activates a downstream protein called PDE.
Both PDE and the transducin G protein are attached to the plasma membrane by a lipid anchor. This
makes them close to each other and facilitates the activation of PDE by the transducin G protein. The
activity of the protein PDE can itself be regulated. It can for example be inhibited by a drug called PDE6i.
7. What…
Chapter 15 Solutions
EBK SEELEY'S ANATOMY & PHYSIOLOGY
Ch. 15.1 - Where are olfactory neurons located? Explain their...Ch. 15.1 - Describe the initiation of an action potential in...Ch. 15.1 - What is unique about olfactory neurons with...Ch. 15.1 - Where are the central olfactory cortex areas...Ch. 15.2 - Name and describe the four kinds of papillae on...Ch. 15.2 - Describe the structure of a taste bud.Ch. 15.2 - What are the five primary tastes? Describe how...Ch. 15.2 - Prob. 8AYPCh. 15.2 - How is the sense of taste related to the sense of...Ch. 15.3 - Prob. 10AYP
Ch. 15.3 - How do the conjunctiva,lacrimal apparatus, and...Ch. 15.3 - Prob. 12AYPCh. 15.3 - How does the pupil constrict? How does it dilate?Ch. 15.3 - Prob. 14AYPCh. 15.3 - Name the three chambers of the eye and the...Ch. 15.3 - Prob. 16AYPCh. 15.3 - Prob. 17AYPCh. 15.3 - Prob. 18AYPCh. 15.3 - Prob. 19AYPCh. 15.3 - Prob. 20AYPCh. 15.3 - Prob. 21AYPCh. 15.3 - Prob. 22AYPCh. 15.3 - Describe the changes that occur in a rod cell...Ch. 15.3 - Prob. 24AYPCh. 15.3 - Prob. 25AYPCh. 15.3 - Prob. 26AYPCh. 15.3 - Prob. 27AYPCh. 15.3 - Prob. 28AYPCh. 15.3 - Starting with the optic nerve, trace the action...Ch. 15.3 - Prob. 30AYPCh. 15.4 - Name the three regions of the ear, and list each...Ch. 15.4 - Describe the relationship among the tympanic...Ch. 15.4 - What are the functions of the external auditory...Ch. 15.4 - Explain how the membranous labyrinth of the...Ch. 15.4 - Describe the structure of the spiral organ.Ch. 15.4 - Explain the differences between inner and outer...Ch. 15.4 - Relate how tip links function.Ch. 15.4 - Prob. 38AYPCh. 15.4 - Contrast volume, pitch, and timbre.Ch. 15.4 - Starting with the auricle, trace a sound wave into...Ch. 15.4 - What is the importance of the sound attenuation...Ch. 15.4 - Prob. 42AYPCh. 15.4 - Describe the neuronal pathways for hearing, from...Ch. 15.4 - Prob. 44AYPCh. 15.4 - Prob. 45AYPCh. 15.4 - What is dynamic equilibrium? Whatstructures are...Ch. 15.4 - Prob. 47AYPCh. 15.4 - Prob. 48AYPCh. 15.5 - Prob. 49AYPCh. 15 - Which of these statements is not true with respect...Ch. 15 - Prob. 2RACCh. 15 - Which of these is not one of the basic tastes? a....Ch. 15 - Which of these types of papillae have no taste...Ch. 15 - Prob. 5RACCh. 15 - The ciliary body a. contains smooth muscles that...Ch. 15 - Prob. 7RACCh. 15 - Prob. 8RACCh. 15 - Prob. 9RACCh. 15 - Prob. 10RACCh. 15 - Prob. 11RACCh. 15 - Prob. 12RACCh. 15 - Prob. 13RACCh. 15 - In the retina cones that are most sensitive to a...Ch. 15 - Given these areas of the retina: (1) macula (2)...Ch. 15 - Prob. 16RACCh. 15 - Prob. 17RACCh. 15 - Which of these structures is found within or is...Ch. 15 - Prob. 19RACCh. 15 - Prob. 20RACCh. 15 - Prob. 21RACCh. 15 - Prob. 22RACCh. 15 - Prob. 23RACCh. 15 - Prob. 24RACCh. 15 - Damage to the semicircular canals affects the...Ch. 15 - Prob. 1CTCh. 15 - Perhaps you have heard that eating carrots is good...Ch. 15 - A man stares at a black clock on a white wall for...Ch. 15 - Prob. 4CTCh. 15 - Prob. 5CTCh. 15 - Prob. 6CTCh. 15 - Professional divers are subject to increased...Ch. 15 - If a vibrating tuning fork is placed against the...
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- Does light striking a photoreceptor results in its depolarization or hypolarization? Why?arrow_forwardEach of the following statements is false. Correct each statement to make it true. a. Activation of rhodopsin depolarizes photoreceptors. b. Activated rhodopsin activates transducin which deactivates cGMP phosphodiesterase. c. Cyclic GMP binds sodium channels, keeping them open, leading to the depolarization of photoreceptor in light.arrow_forwardWhich statement about the events of photoreception is false? a) as a rod cell hyperpolarizes, its release of neurotransmitter increases b) there is more Na+ entry into a rod cell in the dark than in the light c) bipolar cells release more neurotransmitter in the light than in the dark d) as a bipolar cell depolarizes, its release of neurotransmitter increases e) when a rod cell releases neurotransmitter the bipolar cell it synapses with hyperpolarizesarrow_forward
- Which of the following statements about photoreceptors is true? A) There are more rod cells in the fovea of the eye, although overall there are more cones in the human eye. B) All of these options C) Photoreceptors are located near the front of the eye, in the cornea. D) There are two types of photoreceptors, rods and cones, that contain different photopigments.arrow_forwardWhen light strikes a photoreceptor, it reduces the amount of glutamate that it releases. This releases ___ cells from inhibition, allowing them to release more neurotransmitters and excite ___ cells. This produces action potentials that travel down the optic nerve. A) horizontal; amacrine B) amacrine; horizontal C) ganglion; bipolar D) bipolar; ganglionarrow_forwardTransduction of a stimulus usually causes depolarization of a sensory receptor. a.)In most receptors, what is the chemical basis for this depolarization (that is, what is the specific mechanism for the change)?b.)How is a photoreceptor different from other receptors in terms of its membrane potential? c.) Explain how photoreceptors in the light can lead to excitation of some bipolar cells and inhibition of othersarrow_forward
- With what cells do photoreceptors form synapses?arrow_forwardHelp mearrow_forwardHow are Ca2+ channels involved in phototransduction? they cause neurotransmitter release even if no action potentials are produced are not affected by PDE activation in the outer segments when open, they lead to hyperpolarization in photoreceptors in darkness, they do not rely on CGMP levels The density of cones in the retina: is highest where cone outer segments increase in diameter is lowest where retinal blood vessels are absent is drastically less than that of rods in the fovea is indicative of what areas are associated with acuity The recycling of rhodopsin.arrow_forward
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