Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 14.4, Problem 16AYP
Name three types of antimicrobial proteins.
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Important characteristics of antimicrobial drugs include:
a) readily delivered to the site of infection
b) high toxicity against microbial cells
c) do not cause serious side effects in humans
d) remains active in body tissues and fluids
e) all of the above
Explain an example of antimicrobial peptides.
Describe five modes of action for antibiotics. For each, provide one example.
Chapter 14 Solutions
Microbiology: A Systems Approach
Ch. 14.1 - Summarize the three lines of host defenses.Ch. 14.1 - Identify two components of the first line of...Ch. 14.1 - Discuss the role of normal biota as a first-line...Ch. 14.2 - Define marker, and discuss its importance in the...Ch. 14.3 - Prob. 5AYPCh. 14.3 - List the components of the mononuclear phagocyte...Ch. 14.3 - Prob. 7AYPCh. 14.3 - Prob. 8AYPCh. 14.3 - Name six types of blood cells that function in...Ch. 14.3 - Prob. 10AYP
Ch. 14.4 - List the four major categories of nonspecific...Ch. 14.4 - Summarize the steps in phagocytosis, and describe...Ch. 14.4 - Outline the steps in inflammation.Ch. 14.4 - Discuss the mechanism of fever and its role in...Ch. 14.4 - Compare and contrast the three different...Ch. 14.4 - Name three types of antimicrobial proteins.Ch. 14 - Ail example of a nonspecific chemical barrier to...Ch. 14 - Which nonspecific host defense is associated with...Ch. 14 - Prob. 3MCQCh. 14 - Which of the following is not a lymphoid tissue?...Ch. 14 - Prob. 5MCQCh. 14 - Prob. 6MCQCh. 14 - Prob. 7MCQCh. 14 - Prob. 8MCQCh. 14 - Which of the following substances is/are not...Ch. 14 - Which of the following is the end product of the...Ch. 14 - The liquid component of clotted blood is called...Ch. 14 - Prob. 12TFCh. 14 - Prob. 13TFCh. 14 - Prob. 14TFCh. 14 - Prob. 15TFCh. 14 - Prob. 1CTQCh. 14 - Prob. 2CTQCh. 14 - Prob. 3CTQCh. 14 - a. Inflammation is characterized by heat, pain,...Ch. 14 - HIV predominantly infects T helper cells, cells...Ch. 14 - Prob. 1VCCh. 14 - Prob. 1CM
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- Below, you can see a picture of an antimicrobial drug. Regarding semi-synthetic antimicrobial drug development to try to avoid development of antibiotic resistance, use 1 sentence to address what is the significance/value of the presence of the various R-groups (e.g. R4, R5, R6, etc.)?arrow_forwardWhat are antimicrobial peptides?arrow_forwardDefine antispasmodics.arrow_forward
- Given that both human cells and pathogens synthesize proteins at ribosomal sites, how can antimicrobial agents that target this process be safe to use in humans?arrow_forwardThe type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicarrow_forwardList 10 characteristics of an ideal antimicrobial drug.arrow_forward
- Discuss two possible ways that microbes acquire antimicrobial resistance.arrow_forwardWhat is the main group of microorganisms producing the most antibiotics? Describe the biochemical characteristics of this microorganism and provide TWO (2) examples of antibiotics produced by these microbes.arrow_forwardWhat are the 4 main targets of antimicrobials? Provide the rationale why each is a good target.arrow_forward
- Describe four general mechanisms of antimicrobial resistance.arrow_forwardBroad-spectrum drugs target a wide variety of bacterial pathogens. Even when the broad-spectrum drug is capable of killing a target pathogen, it may not be the best treatment. Which statement best explains why a broad spectrum drug might be an undesirable treatment choice? Broad-spectrum antimicrobials are usually toxic to the host cells. Broad-spectrum antimicrobials only work if they are used shortly after the infection begins. Broad-spectrum antimicrobials may kill much of the normal microbiota. Broad-spectrum antimicrobials are not able to kill bacteria that are in their log phase of growth. Broad-spectrum antimicrobials may stimulate excess growth of the normal microbiota.arrow_forwardWhat bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.arrow_forward
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