Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 14, Problem 59TQ
Summary Introduction

To review:

The source of the nitrogen atom in purine nucleotide synthesis.

Introduction:

Purines are synthesized by de novo synthesis. This synthesis starts with the formation of PRPP (5-phosph-α-d-ribosyl-1-pyrophosphate). The synthesis of PRPP is catalyzed by ribose-5-phosphate pyrophosphatase. Purine synthesis also takes place through the salvage pathway.

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