Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 12.4, Problem 6R
Summary Introduction
To review:
The linked genes from the data and the distance between them in map units.
Introduction:
Linked genes are those, which get inherited together and do not follow the normal
The cross results of three autosomal characteristics in Drosophila, namely, the body color, wings shape, and eye color are as follows:
Cross I:
Parents: Heterozygous red eye color, normal wings × sepia eye color, vestigial wings.
Offspring results:
131 | Red-eye color, Normal wings |
120 | Sepia eye color, Vestigial wings |
122 | Red-eye color, Vestigial wings |
127 | Sepia eye color, Normal wings |
Cross II:
Parents: Heterozygous gray body, normal wings × black body color, vestigial wings.
Offspring results:
236 | Gray body, normal wings. |
253 | Black body, Vestigial wings. |
50 | Gray body, Vestigial wings. |
61 | Black body, Normal wings. |
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Another cross in Drosophila involved the recessive, X-linked genes yellow (y), white (w) and cut (ct). A yellow-bodied, white-eyed female with normal wings was crossed to a male whose eyes and body were normal but whose wings were cut. The F1 females were wild type for all three traits, while the F1 males expressed the yellow-body and white eyes traits. The cross was carried to an F2 progeny and only male offspring were tallied. Based on the data shown here, a genetic map was constructed. a) Diagram the genotypes of the F1 parents. b) Construct a map, assuming the white is at locus 1.5 on the X-chromosome.
Phenotype
Male offspring
y + ct
9
+ w +
6
y w ct
90
+ + +
95
+ + ct
424
y w +
376
y + +
0
+ w ct
0
Another cross in Drosophila involved the recessive, X-linked genes yellow (y), white (w) and cut (ct). A yellow-bodied, white-eyed female with normal wings was crossed to a male whose eyes and body were normal but whose wings were cut. The F1 females were wild type for all three traits, while the F1 males expressed the yellow-body and white eyes traits. The cross was carried to an F2 progeny and only male offspring were tallied. Based on the data shown here, a genetic map was constructed. a) Diagram the genotypes of the F1 parents. b) Construct a map, assuming the white is at locus 1.5 on the X-chromosome
*******ANSWER PART B NOT PART A!!!!
Phenotype
Male offspring
y + ct
9
+ w +
6
y w ct
90
+ + +
95
+ + ct
424
y w +
376
y + +
0
+ w ct
0
In Drosophila melanogaster, red eyes are dominant over white and the variation for this characteristic is on the X chromosome. Vestigial wings (v) are recessive to normal (V) for an autosomal gene. Predict the appearance of offspring of the following crosses: XW/XwV/v×Xw/Y v/v, Xw/XwV/v×XW/Y V/v.
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Life: The Science of Biology
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- In Drosophila fruit flies, the genes for warped wings (dwp), rumpled bristles (rmp), and pallid wings (pld) are linked. A trihybrid female for all three allleles is crossed with homozygous recessive male for all three alleles and the offspring obtained showed the following phenotypes: 3 pld rmp dwp 428 pld rmp + 427 + + dwp 48 + rmp + 47 pld + dwp 23 pld + + 2 + + + 22 + rmp dwp What is the order and map distance between these three alleles?arrow_forwardIn Drosophila, a cross was made between females—all expressing the three X-linked recessive traits scute bristles (sc), sable body (s), and vermilion eyes (v)—and wild-type males. In the F1, all females were wild type, while all males expressed all three mutant traits. The cross was carried to the F2 generation, and 1000 offspring were counted, with the results shown in the following table. Phenotype Offspring sc s v 314 + + + 280 + s v 150 sc + + 156 sc + v 46 + s + 30 sc s + 10 + + v 14 No determination of sex was made in the data. (a) Using proper nomenclature, determine the genotypes of the P1 and F1 parents. (b) Determine the sequence of the three genes and the map distances between them. (c) Are there more or fewer double crossovers than expected? (d) Calculate the coefficient of coincidence. Does it represent positive or negative interference?arrow_forwardIn the fruit fly Drosophila melanogaster, the following genes and mutations are known:Wing size: recessive allele for tiny wings t; dominantallele for normal wings T.Eye shape: recessive allele for narrow eyes n;dominant allele for normal (oval) eyes N.For each of the four following crosses, give thegenotypes of each of the parents.Male FemaleWings Eyes Wings Eyes Offspring1 tiny oval × tiny oval 78 tiny wings, oval eyes24 tiny wings, narrow eyes2 normal narrow × tiny oval 45 normal wings, oval eyes40 normal wings, narrow eyes38 tiny wings, oval eyes44 tiny wings, narrow eyes3 normal narrow × normal oval 35 normal wings, oval eyes29 normal wings, narrow eyes10 tiny wings, oval eyes11 tiny wings, narrow eyes4 normal narrow × normal oval 62 normal wings, oval eyes19 tiny wings, oval eyesarrow_forward
- In Drosophila melanogaster, vestigial (short) wings (vg) are caused by a recessive mutant gene that independently assorts with a gene pair that influences body hair. Hairy (h ) results in a hairy body. A cross is made between a fly with normal wings and a hairy body and a fly with vestigial wings and a normal body. The phenotypically normal F1 flies were crossed among each other and 1024 F2 flies were reared. What phenotypes would you expect in the F2 and in what actual numbers (not ratio) would you expect to find them?arrow_forwardIn roses, purple flower color is determined by the dominant P allele, while pphomozygotes are white. The presence of long stems is determined by the dominant S allele, while ss homozygotes have short stems. Both mutations are completely penetrant. A test cross was performed between a rose plant of unknown genotype with a white flowered, short stemmed rose plant (pp ss) and the following 200 progeny plants were obtained: 84 white flowers, long stems 16 purple flowers, long stems 82 purple flowers, short stems 18 white flowers, short stems Select two statements below that are TRUE. options: The P and S genes independently assort during meiosis. The map distance between P and S is 17 cM. The genotype of the progeny plants with purple flowers and short stems is PP ss. The map distance between P and S is 83 cM. The homologs in the plant with…arrow_forwardIn Drosophila, white eyes (w) are recessive to red eyes (w+) at one locus and black body (b) is recessive to gray body (b+). A homozygous white eyes, gray bodied female is crossed with a homozygous red eyes, black bodied male to produce the F1 progeny. The F1 progeny are testcrossed and produce the following progeny: White eyes, black body: 212 White eyes, gray body: 288 Red eyes, black body: 308 Red eyes, gray body: 192 Does the evidence indicate that w and b loci are linked? Explain why or why not? If they are linked, what is the map distance between the two loci? If they are not linked, what is the map distance between the two loci? If they are linked, are the allels in the F1 in coupling or repulsion? How do you know? Draw the genotypes of all individuals described in the problem (original parents, F1, testcross, and F2 progeny) using the appropriate notation.arrow_forward
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